Imatinib D4
| Product Name | Imatinib D4 |
|---|---|
| Alternate Names | Imatinib Stable Isotopes, Stable Isotopes of Imatinib |
| CAT No. | CS-O-02701 |
| CAS No. | 1134803-16-9 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 497.63 g/mol |
| Mol. For. | C₂₉H₂₇D₄N₇O |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Imatinib |
| Purity | 95% |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CC1=CC=C(NC(C(C([2H])=C2[2H])=C(C([2H])=C2CN3CCN(C)CC3)[2H])=O)C=C1NC4=NC=CC(C5=CN=CC=C5)=N4 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Imatinib D4 is a deuterated form of Imatinib, which is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs), and other types of cancer. Imatinib D4 is chemically identical to Imatinib, except that it contains four deuterium atoms in place of hydrogen atoms. This isotopic substitution results in a slightly higher molecular weight, which can improve the drug's pharmacokinetics and pharmacodynamics.
Imatinib D4 works by inhibiting the activity of BCR-ABL, a fusion protein that is overproduced in CML and drives the growth of cancer cells. By blocking this protein, Imatinib D4 can slow or stop the proliferation of cancer cells, leading to remission or extended survival in many patients.
The usage of Imatinib D4 is similar to that of Imatinib, with the main difference being its isotopic composition. The drug is typically administered orally, in the form of tablets or capsules, with dosages varying depending on the patient's condition and response to treatment. Side effects of Imatinib D4 may include nausea, vomiting, diarrhea, muscle cramps, and fatigue.
In terms of chemical information, Imatinib D4 has a molecular formula of C29H29D4N7O and a molecular weight of 505.65 g/mol. It is a white to off-white powder that is insoluble in water but soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO). Imatinib D4 is stable under normal storage conditions and can be stored at room temperature for extended periods of time.
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Related Compounds
Imatinib 13C D3 | Imatinib-(4-desmethyl phenyl)-impurity-d4 | N-Desmethyl Imatinib D8 | Imatinib D8 | Desmethyl imatinib D4 | Gleevec-d8 Mesylate (Imatinib-d8 Mesylate) | Imatinib Para-diaminomethylbenzene Impurity-d3 | Imatinib D3 |