Nebivolol D4

Product Name Nebivolol D4
Alternate Names Nebivolol Stable Isotopes, Stable Isotopes of Nebivolol
CAT No. CS-O-02703
CAS No. 118457-14-0(Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 409.46 g/mol
Mol. For. C₂₂H₂₁D₄F₂NO₄
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nebivolol
Purity 95%
Smileys O[C@H]([C@]1([H])OC2=CC=C(F)C=C2CC1)C([2H])([2H])NC([2H])([2H])[C@@H]([C@@]3([H])OC4=CC=C(F)C=C4CC3)O
Canonical Smiles C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O
InchIKey KOHIRBRYDXPAMZ-YHDSQAASSA-N
Inchl InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2/t17-,18-,21-,22+/m0/s1
IUPAC (1S)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol
Controlled No
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Nebivolol D4 is a synthetic compound that is a deuterated version of the beta-blocker drug Nebivolol. It is commonly used as a reference standard in pharmacological research and is used to evaluate the efficacy of Nebivolol in biological systems. Nebivolol D4 has the same chemical structure as Nebivolol but has four deuterium atoms attached to the molecule instead of hydrogen atoms. Deuterium is a stable isotope of hydrogen and is often used as a labeling tool in pharmacology research. Nebivolol D4 works by blocking the beta-adrenergic receptors in the heart and blood vessels, resulting in a decrease in heart rate and blood pressure. This makes Nebivolol D4 an effective treatment for hypertension and other cardiovascular diseases. It is also used to treat angina and heart failure. Nebivolol D4 is metabolized in the liver and excreted in the urine. The chemical formula for Nebivolol D4 is C22H27D4NO4, and it has a molecular weight of 391.52 g/mol. It is a white crystalline powder that is soluble in methanol and ethanol. The melting point of Nebivolol D4 is around 105-108°C. In conclusion, Nebivolol D4 is a useful tool in pharmacological research and is an effective treatment for various cardiovascular diseases. Its chemical structure and properties make it a valuable reference standard for evaluating the efficacy of Nebivolol in biological systems.

Related Compounds

Nebivolol (RSSS) -D4 | R-Nebivolol D4 HCl | rac Nebivolol D8 | Nebivolol(SRRR)-D4 | Nebivolol-d4-O-D-Glucuronide (Mixture of Diastereomers) | rac-Nebivolol-D6 |

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