Repaglinide D5

Product Name Repaglinide D5
Alternate Names Repaglinide Stable Isotopes, Stable Isotopes of Repaglinide
CAT No. CS-O-02744
CAS No. 1217709-85-7
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 457.62 g/mol
Mol. For. C₂₇H₃₁D₅N₂O₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Repaglinide
Purity 98.36
Therapeutic Anti-Diabetic
Smileys O=C(CC1=CC(OC([2H])([2H])C([2H])([2H])[2H])=C(C(O)=O)C=C1)N[C@H](C2=C(N3CCCCC3)C=CC=C2)CC(C)C
Canonical Smiles CCOC1=C(C=CC(=C1)CC(=O)NC(CC(C)C)C2=CC=CC=C2N3CCCCC3)C(=O)O
InchIKey FAEKWTJYAYMJKF-NTSVIFQKSA-N
Inchl InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1/i1D3,4D2
IUPAC 4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]-2-(1,1,2,2,2-pentadeuterioethoxy)benzoic acid
Controlled No
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Repaglinide D5 is a stable isotope-labeled analog of the anti-diabetic drug repaglinide, which is used to treat type 2 diabetes. It belongs to the class of medications known as meglitinides, which stimulate insulin secretion from the pancreas in response to food intake. Repaglinide D5 contains five deuterium atoms in the molecular structure, which allows for accurate quantitative analysis in biological samples using mass spectrometry-based techniques. The recommended dosage of repaglinide D5 is the same as that of repaglinide, which varies depending on individual patient needs and response. It is typically taken orally before meals to control blood glucose levels. As with any medication, it is important to follow the instructions provided by a healthcare professional and not to exceed the recommended dosage. The chemical formula of repaglinide D5 is C27H28D5NO4, and its molecular weight is 449.62 g/mol. It has a melting point of 138-140°C and is soluble in organic solvents such as methanol, ethanol, and acetonitrile. The drug works by binding to ATP-sensitive potassium channels on the surface of pancreatic beta cells, which leads to an influx of calcium ions and subsequent insulin release. It has a relatively short half-life of about 1 hour and is metabolized by the liver and excreted in the urine and feces. Repaglinide D5 is generally well-tolerated, but it may cause side effects such as hypoglycemia, headache, and nausea.

Related Compounds

Repaglinide M1-D5 | Repaglinide M2-D5 |

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