Atazanavir D6

Chemical Name Atazanavir D6
Alternate Names Atazanavir Stable Isotopes, Stable Isotopes of Atazanavir
CAT No. CS-O-02748
CAS Registry# 1092540-50-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 710.89 g/mol
Mol. For. C₃₈H₄₆D₆N₆O₇
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Atazanavir
Purity 95%
Therapeutic Antiretroviral / Anti-HIV
Smileys CC(C)(C)C(C(=O)NC(CC1=CC=CC=C1)C(CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)C(C(C)(C)C)NC(=O)OC)O)NC(=O)OC
Canonical Smiles CC(C)(C)C(C(=O)NC(CC1=CC=CC=C1)C(CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)C(C(C)(C)C)NC(=O)OC)O)NC(=O)OC
InchIKey AXRYRYVKAWYZBR-ORLNJQPYSA-N
Inchl InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1/i7D3,8D3
IUPAC trideuteriomethyl N-[(2S)-1-[2-[(2S,3S)-3-[[(2S)-3,3-dimethyl-2-(trideuteriomethoxycarbonylamino)butanoyl]amino]-2-hydroxy-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
Controlled No
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Atazanavir D6 is a deuterated form of the antiretroviral drug Atazanavir. It is a protease inhibitor that is used in the treatment of HIV-1 infections. The deuterated form of Atazanavir is designed to have improved pharmacokinetic properties, making it more effective and safer to use than the non-deuterated form. Atazanavir D6 works by blocking the action of the HIV-1 protease enzyme, which is essential for the replication of the virus. This prevents the virus from multiplying and reduces the amount of virus in the body, leading to a decrease in the progression of the disease. The chemical structure of Atazanavir D6 is similar to that of the non-deuterated form, with the addition of six deuterium atoms in the molecule. Deuterium is a naturally occurring isotope of hydrogen, which has one extra neutron in its nucleus. This increase in molecular weight results in a slower metabolism and elimination of the drug from the body, leading to increased bioavailability and longer half-life. Atazanavir D6 is administered orally in the form of capsules or tablets and is usually taken once daily with food. The recommended dose may vary depending on the patient's age, weight, and medical condition. It is important to follow the dosage instructions given by the healthcare provider to ensure the effectiveness and safety of the drug. In conclusion, Atazanavir D6 is a deuterated form of Atazanavir, which is used in the treatment of HIV-1 infections. Its chemical structure is modified to improve its pharmacokinetic properties, making it more effective and safer to use. It works by blocking the HIV-1 protease enzyme, which prevents the virus from multiplying and reduces the progression of the disease. Atazanavir D6 is administered orally and must be taken once daily with food, following the dosage instructions given by the healthcare provider.

Related Compounds

Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir-d5 | Atazanavir D4 | Des-N-(methoxycarbonyl)-L-tert-leucine Atazanavir-d5 Trihydrochloride | Atazanavir D18 | Atazanavir D9 | Atazanavir D24 |

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