Quetiapine D4 (Ethanol-d4) fumarate

Quetiapine D4 (Ethanol-d4) fumarate is a deuterated form of Quetiapine, a medication that is used to treat mental/mood disorders such as schizophrenia and bipolar disorder. Quetiapine D4 is a labeled compound that has four deuterium atoms replacing the hydrogen atoms in the molecule, which makes it useful for drug metabolism studies and clinical research. The primary mechanism of action of Quetiapine is through antagonism of dopamine and serotonin receptors in the brain. This drug acts as an antagonist at dopamine D1, D2, D3, and serotonin 5-HT1A and 5-HT2A receptors. It also has mild antagonism at histamine H1 and alpha-1 adrenergic receptors. This combination of receptor antagonism results in the therapeutic effects of Quetiapine. Quetiapine D4 fumarate is available in tablet form for oral administration and should be taken once or twice a day depending on the patient's condition. The recommended starting dose is 25mg per day, and the dose can be gradually increased to achieve the desired effect. Like all medications, Quetiapine D4 fumarate has potential side effects, including drowsiness, dizziness, dry mouth, weight gain, and constipation. It is important to follow the prescribed dosage and report any adverse reactions to a healthcare provider. Overall, Quetiapine D4 fumarate is a useful tool for clinical research and drug metabolism studies, and it is an effective medication for the treatment of mental/mood disorders when used as directed.