2-hydroxy Desipramine D3

Product Name 2-hydroxy Desipramine D3
Alternate Names Desipramine Stable Isotopes, Stable Isotopes of Desipramine
CAT No. CS-O-02795
CAS No. 1189998-63-7
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 285.39 g/mol
Mol. For. C18H19D3N2O
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Desipramine
Purity 98
Smileys OC1=CC=C2N(C3=CC=CC=C3CCC2=C1)CCCNC([2H])([2H])[2H]
Canonical Smiles CNCCCN1C2=C(CCC3=CC=CC=C31)C=C(C=C2)O
InchIKey NVJBOLMRGMDGLD-FIBGUPNXSA-N
Inchl InChI=1S/C18H22N2O/c1-19-11-4-12-20-17-6-3-2-5-14(17)7-8-15-13-16(21)9-10-18(15)20/h2-3,5-6,9-10,13,19,21H,4,7-8,11-12H2,1H3/i1D3
IUPAC 11-[3-(trideuteriomethylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol
Controlled No
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2-hydroxy Desipramine D3, also known as 2-hydroxy desmethylimipramine D3, is a stable isotope-labeled compound that is commonly used in research and clinical studies as an internal standard or reference material for the quantification of desipramine and its metabolites in biological samples. Desipramine is a tricyclic antidepressant that works by increasing the levels of norepinephrine in the brain, which helps to elevate mood and reduce symptoms of depression. 2-hydroxy Desipramine D3 is a metabolite of desipramine that is formed in the liver and excreted in urine. The chemical formula of 2-hydroxy Desipramine D3 is C18H18D3ClN2O, and it has a molecular weight of 307.83 g/mol. It is a white to off-white crystalline powder that is soluble in organic solvents like methanol, ethanol, and acetonitrile. The usage of 2-hydroxy Desipramine D3 is mainly focused on pharmacokinetic and pharmacodynamic studies, where it is used to determine the metabolism, bioavailability, and elimination of desipramine in humans and animals. It is also used as a calibration standard in analytical methods like liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the quantification of desipramine and its metabolites in biological fluids. Overall, 2-hydroxy Desipramine D3 is a valuable tool in the field of pharmacology and toxicology, as it enables accurate and precise measurement of desipramine and its metabolites, which is critical for understanding the safety and efficacy of these drugs.

Related Compounds

Desipramine Hydrochloride D3 | Desipramine-2,4,6,8-d4 Hydrochloride | Desipramine D3 | Desipramine D6 |

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