Artemether D3
| Product Name | Artemether D3 |
|---|---|
| Alternate Names | Artemether Stable Isotopes, Stable Isotopes of Artemether |
| CAT No. | CS-O-02874 |
| CAS No. | 93787-85-0 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 301.39 g/mol |
| Mol. For. | C₁₆H₂₃D₃O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Artemether |
| Purity | 95% |
| Smileys | CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C |
| Canonical Smiles | CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C |
| InchIKey | SXYIRMFQILZOAM-SAMIBWLCSA-N |
| Inchl | InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1/i4D3 |
| IUPAC | (1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-10-(trideuteriomethoxy)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Artemether D3 is a synthetic derivative of artemisinin, a natural product isolated from the Chinese medicinal plant Artemisia annua. It is a potent antimalarial drug used in the treatment of uncomplicated malaria caused by Plasmodium falciparum, a species of the parasite that is resistant to many other antimalarial drugs. The addition of three deuterium atoms to the structure of artemether allows for its use as a stable isotope internal standard in pharmacokinetic studies.
Artemether D3 acts by inhibiting the growth and replication of the malaria parasite in the blood. Its mechanism of action involves the formation of free radicals and the generation of reactive oxygen species, which damage the parasite's cell membrane and proteins, leading to its death. The drug is effective against both the blood stages and the liver stages of the parasite's life cycle, making it an important tool in the fight against malaria.
The recommended dosage of artemether D3 varies depending on the age and weight of the patient, as well as the severity of the infection. It is typically administered in combination with another antimalarial drug, such as lumefantrine or mefloquine, to reduce the risk of drug resistance. The drug is generally well-tolerated, although some common side effects include nausea, vomiting, and dizziness.
In conclusion, artemether D3 is a potent and effective antimalarial drug that is widely used in the treatment of malaria. Its stable isotope properties make it an important tool in pharmacokinetic studies, and its mechanism of action is well-understood. With continued research and development, artemether D3 may play an increasingly important role in the fight against malaria and other parasitic diseases.
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Related Compounds
Artemether 13C D3 |