Hydrocortisone D4

Product Name Hydrocortisone D4
Alternate Names Hydrocortisone Stable Isotopes, Stable Isotopes of Hydrocortisone
CAT No. CS-O-02905
CAS No. 73565-87-4
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 366.48 g/mol
Mol. For. C21H26D4O5
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Hydrocortisone
Purity 95%
Therapeutic Immunosuppressants
Smileys C[C@@]1([C@@]2(O)C(CO)=O)[C@](CC2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(CC4)C)([2H])[C@](O)([2H])C1([2H])[2H]
Canonical Smiles CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
InchIKey JYGXADMDTFJGBT-LTVXCZLVSA-N
Inchl InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15?,16-,18?,19-,20-,21?/m0/s1/i10D2,16D,18D
IUPAC (8S,10R,11S,13S)-9,11,12,12-tetradeuterio-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Controlled No
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Hydrocortisone D4 is a synthetic variant of the naturally occurring hormone hydrocortisone, also known as cortisol. It is a potent anti-inflammatory and immunosuppressive agent that is commonly used in the treatment of a wide range of inflammatory and autoimmune disorders such as eczema, psoriasis, and rheumatoid arthritis. The chemical structure of Hydrocortisone D4 is similar to that of hydrocortisone, except that it contains four deuterium atoms. Deuterium is an isotope of hydrogen that has a slightly higher atomic mass, which makes Hydrocortisone D4 useful in pharmacokinetic studies and drug metabolism research. Hydrocortisone D4 is typically administered topically as a cream, ointment, or lotion, although it can also be given orally or by injection in more severe cases. It works by binding to glucocorticoid receptors in cells throughout the body, which leads to a reduction in inflammation and immune system activity. Like all medications, Hydrocortisone D4 does carry some risk of side effects. These can include skin irritation, thinning of the skin, and increased susceptibility to infection. However, when used as directed by a healthcare professional, Hydrocortisone D4 is generally considered to be safe and effective for treating a variety of inflammatory and autoimmune disorders.

Related Compounds

Allotetrahydrocortisone-[d5] | Allotetrahydrocortisone-[D4] | Allotetrahydrocortisone-[d5] (Solution) | Tetrahydrocortisone-2,2,3,4,4-D5 | Cortisol-[d4] |

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