Piroxicam D3

Product Name Piroxicam D3
Alternate Names Piroxicam Stable Isotopes, Stable Isotopes of Piroxicam
CAT No. CS-O-02991
CAS No. 942047-64-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 334.36 g/mol
Mol. For. C15H10D3N3O4S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Piroxicam
Purity 99.86
Smileys OC(C1=CC=CC=C1[S]2(=O)=O)=C(N2C([2H])([2H])[2H])C(NC3=CC=CC=N3)=O
Canonical Smiles CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
InchIKey QYSPLQLAKJAUJT-FIBGUPNXSA-N
Inchl InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)/i1D3
IUPAC 4-hydroxy-1,1-dioxo-N-pyridin-2-yl-2-(trideuteriomethyl)-1lambda6,2-benzothiazine-3-carboxamide
Controlled No
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Piroxicam D3 is a deuterated derivative of the non-steroidal anti-inflammatory drug (NSAID) piroxicam. It has identical pharmacological properties to piroxicam, but with the added benefit of being useful in pharmacokinetic studies due to its unique deuterium label. Piroxicam D3 is used in the treatment of a wide range of conditions including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other inflammatory conditions. It works by inhibiting the production of prostaglandins, which are responsible for causing inflammation and pain. The chemical structure of Piroxicam D3 is similar to that of piroxicam, but with three deuterium atoms substituted for hydrogen atoms. This makes it a useful tool in pharmacokinetic studies as it allows researchers to track the movement and metabolism of the drug within the body. The deuterium label does not affect the pharmacological activity of the drug, and it is safe for use in humans. Piroxicam D3 is typically administered orally in the form of capsules or tablets. It is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations reached within 3-5 hours. The drug is metabolized in the liver and excreted primarily in the urine. The half-life of Piroxicam D3 is approximately 50 hours, meaning that it stays in the body for a relatively long time compared to other NSAIDs. This prolonged half-life allows for less frequent dosing, which can be more convenient for patients.

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