Teriflunomide D4

Product Name Teriflunomide D4
Alternate Names Teriflunomide Stable Isotopes, Stable Isotopes of Teriflunomide
CAT No. CS-O-03076
CAS No. 1185240-22-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 274.23 g/mol
Mol. For. C₁₂H₅D₄F₃N₂O₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Teriflunomide
Purity 95%
Therapeutic Immunosuppressants
Smileys CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O
Canonical Smiles CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O
InchIKey UTNUDOFZCWSZMS-QFFDRWTDSA-N
Inchl InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/i2D,3D,4D,5D
IUPAC 2-cyano-3-hydroxy-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]but-2-enamide
Controlled No
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Teriflunomide D4 is a deuterated version of the drug Teriflunomide, which is used to treat relapsing multiple sclerosis. It works by inhibiting an enzyme called dihydroorotate dehydrogenase, which is necessary for the proliferation of T and B lymphocytes. This results in a decrease in the inflammatory response in the central nervous system, which is a key factor in the development of multiple sclerosis. Teriflunomide D4 is used in research and clinical settings as a stable isotopic internal standard for the quantification of Teriflunomide in biological samples. Deuterated compounds are used as internal standards because they have identical chemical properties to their non-deuterated counterparts, but have a different mass. This allows for accurate and precise measurement of the drug in samples, as the deuterated internal standard can be easily distinguished from the endogenous compound. The chemical formula for Teriflunomide D4 is C12H7D4F3N2O2, and it has a molecular weight of 279.24 g/mol. It is a white to off-white powder that is soluble in dimethyl sulfoxide, ethanol, and acetonitrile. In conclusion, Teriflunomide D4 is a valuable tool in the quantification of Teriflunomide in biological samples, and its usage in research and clinical settings is important for understanding the pharmacokinetics and pharmacodynamics of this drug in the treatment of multiple sclerosis.

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