3-Demethyl Thiocolchicine D3

Product Name 3-Demethyl Thiocolchicine D3
Alternate Names Colchicine Stable Isotopes, Stable Isotopes of Colchicine
CAT No. CS-O-03104
CAS No. 1246818-03-0
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 404.49 g/mol
Mol. For. C₂₁H₂₀D₃NO₅S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Colchicine
Purity 95%
Smileys CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)O
Canonical Smiles CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)O
InchIKey PKYOHQGXPPVIGD-VSLDJYOXSA-N
Inchl InChI=1S/C21H23NO5S/c1-11(23)22-15-7-5-12-9-17(25)20(26-2)21(27-3)19(12)13-6-8-18(28-4)16(24)10-14(13)15/h6,8-10,15,25H,5,7H2,1-4H3,(H,22,23)/t15-/m0/s1/i1D3
IUPAC 2,2,2-trideuterio-N-[(7S)-3-hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Controlled No
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3-Demethyl Thiocolchicine D3 is a naturally occurring compound that belongs to the family of colchicine alkaloids. It is a derivative of Thiocolchicine, which is a well-known anti-tumor and anti-inflammatory agent. 3-Demethyl Thiocolchicine D3 has a similar structure to Thiocolchicine, but with one less methyl group. This structural difference makes it a potent analog of Thiocolchicine, with improved bioavailability and therapeutic efficacy. The compound has been studied for its anti-tumor and anti-inflammatory properties. It is known to inhibit the formation of microtubules, which are essential for cell division and growth. As a result, it can prevent the proliferation of cancer cells and reduce inflammation. It has been studied in vitro and in vivo for its efficacy against various types of cancer, including breast cancer, ovarian cancer, and lung cancer. 3-Demethyl Thiocolchicine D3 is also being studied for its potential as a treatment for gout and other inflammatory diseases. It has been shown to reduce the production of pro-inflammatory cytokines, which are responsible for the inflammation associated with gout and other inflammatory diseases. In terms of chemical information, 3-Demethyl Thiocolchicine D3 has a molecular formula of C21H23NO5 and a molecular weight of 369.41 g/mol. It has a melting point of 230-232 °C and is soluble in organic solvents such as ethanol, methanol, and chloroform. Its chemical structure consists of a colchicine skeleton with a demethylated group at the C-3 position.

Related Compounds

Colchicine 13C D3 | Colchicine D6 | iso-Colchicine-d3 | Colchicine D3 |

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