Enalaprilat-d5 (phenyl-d5)
| Product Name | Enalaprilat-d5 (phenyl-d5) |
|---|---|
| Alternate Names | Enalapril Stable Isotopes, Stable Isotopes of Enalapril |
| CAT No. | CS-O-03157 |
| CAS No. | 349554-00-3 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 353.43 g/mol |
| Mol. For. | C₁₈H₁₉D₅N₂O₅ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Enalapril |
| Purity | 95% |
| Therapeutic | Anti-Hypertensives |
| Smileys | CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O |
| Canonical Smiles | CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O |
| InchIKey | LZFZMUMEGBBDTC-CHNCPRCNSA-N |
| Inchl | InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14+,15-/m0/s1/i2D,3D,4D,6D,7D |
| IUPAC | (2S)-1-[(2S)-2-[[(1R)-1-carboxy-3-(2,3,4,5,6-pentadeuteriophenyl)propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Enalaprilat-d5 (phenyl-d5) is a deuterated form of Enalaprilat, which is a medication used to treat hypertension, heart failure, and diabetic kidney disease. Enalaprilat is a prodrug that is converted to its active form, Enalaprilat, in the liver. Enalaprilat-d5 (phenyl-d5) is chemically identical to Enalaprilat but has five deuterium atoms in the phenyl group, which makes it useful in pharmacokinetic studies and drug metabolism research.
Enalaprilat-d5 (phenyl-d5) can be administered intravenously to patients who cannot take oral medication. The medication works by inhibiting the angiotensin-converting enzyme (ACE), which is responsible for converting angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor that raises blood pressure. By inhibiting ACE, Enalaprilat-d5 (phenyl-d5) reduces the levels of angiotensin II, resulting in vasodilation and lowered blood pressure.
Enalaprilat-d5 (phenyl-d5) has a half-life of approximately 1.3 hours and is eliminated primarily through renal excretion. The deuterium labeling on the phenyl group does not affect the pharmacological properties of Enalaprilat-d5 (phenyl-d5), but it does allow for accurate measurements of drug levels in the body and the study of drug metabolism.
Overall, Enalaprilat-d5 (phenyl-d5) is a useful tool in pharmacokinetic and drug metabolism research. Its chemical properties and pharmacological effects make it an effective medication for treating hypertension and heart failure.
Get an Instant Quote
Related Compounds
Enalaprilat D5 maleate | Enalapril D5 | Enalaprilat D5 Sodium Salt | Enalapril-d5 tert-Butyl Ester | Enalapril-d3 | Enalapril D5 maleate |