Azathioprine 13C4
| Product Name | Azathioprine 13C4 |
|---|---|
| Alternate Names | Azathioprine Stable Isotopes, Stable Isotopes of Azathioprine |
| CAT No. | CS-O-03166 |
| CAS No. | 1346600-71-2 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Azathioprine |
| Therapeutic | Immunosuppressants |
| Smileys | [13CH3]N1[13C](SC2=C(NC=N3)C3=NC=N2)=[13C](N=[13CH]1)[N](=O)=O |
| Canonical Smiles | CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-] |
| InchIKey | LMEKQMALGUDUQG-HXRDNURUSA-N |
| Inchl | InChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)/i1+1,4+1,7+1,9+1 |
| IUPAC | 6-(3-(113C)methyl-5-nitro(2,4,5-13C3)imidazol-4-yl)sulfanyl-7H-purine |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Azathioprine 13C4 is a medication used to treat autoimmune diseases such as rheumatoid arthritis, Crohn's disease, and lupus. It is also used to prevent rejection in certain types of organ transplants. The drug works by suppressing the immune system, which reduces inflammation and helps to prevent tissue damage. Azathioprine 13C4 is a stable isotope-labeled version of the drug, which is used in research studies to track the metabolism of the drug in the body.
Chemically, Azathioprine 13C4 is a purine analog that inhibits the synthesis of DNA and RNA. It is metabolized in the liver to its active form, 6-mercaptopurine (6-MP), which is then converted to its active metabolite, 6-thioguanine nucleotides (6-TGNs). The concentration of 6-TGNs in the body is directly related to the therapeutic efficacy of the drug.
The dosage of Azathioprine 13C4 varies depending on the condition being treated and the patient's individual needs. The drug is usually taken orally once or twice a day, with or without food. Patients taking Azathioprine 13C4 should be monitored regularly for side effects, including nausea, vomiting, diarrhea, and liver toxicity. The drug should not be used during pregnancy or while breastfeeding.
In conclusion, Azathioprine 13C4 is a medication used to treat autoimmune diseases and prevent organ transplant rejection. It works by suppressing the immune system and inhibiting DNA and RNA synthesis. The drug is metabolized in the liver to its active form and should be taken under close medical supervision.
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Related Compounds
Azathioprine-13C2-15N | Azathioprine-d3 |