Cycloguanil D6 Hydrochloride
| Product Name | Cycloguanil D6 Hydrochloride |
|---|---|
| Alternate Names | Cycloguanil Stable Isotopes, Stable Isotopes of Cycloguanil |
| CAT No. | CS-O-03225 |
| CAS No. | 152-53-4(Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 294.21 g/mol |
| Mol. For. | C₁₁H₉D₆Cl₂N₅ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Cycloguanil |
| Purity | 98.99 |
| Smileys | NC1=NC(N)=NC(N1C2=CC=C(Cl)C=C2)(C([2H])([2H])[2H])C([2H])([2H])[2H].Cl |
| Canonical Smiles | CC1(N=C(N=C(N1C2=CC=C(C=C2)Cl)N)N)C.Cl |
| InchIKey | MOUAPRKJJUXEIE-UHFFFAOYSA-N |
| Inchl | InChI=1S/C11H14ClN5.ClH/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8;/h3-6H,1-2H3,(H4,13,14,15,16);1H |
| IUPAC | 1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine;hydrochloride |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Cycloguanil D6 Hydrochloride is a deuterated derivative of cycloguanil, which is a potent anti-malarial agent. The deuterium-labeled compound is used as an internal standard in mass spectrometry-based pharmacokinetic studies of cycloguanil. It is an essential tool for determining the concentration of the drug in biological samples accurately.
The chemical formula of Cycloguanil D6 Hydrochloride is C13H11D6Cl2N5. The compound has a molecular weight of 323.17 g/mol. It is a white crystalline powder that is soluble in water and alcohol. The compound has a melting point of 214-218°C.
Cycloguanil D6 Hydrochloride is a potent inhibitor of dihydrofolate reductase (DHFR) enzymes. It acts by inhibiting the synthesis of folate, which is essential for the growth and replication of the malaria parasite. The compound is effective against both chloroquine-resistant and chloroquine-sensitive strains of Plasmodium falciparum, the causative agent of malaria.
Cycloguanil D6 Hydrochloride is used in combination with other antimalarial drugs to treat uncomplicated and severe malaria. The compound is administered orally, and the dosage depends on the age and weight of the patient. The drug is well-tolerated, and the most common side effects are nausea, vomiting, and headache.
In conclusion, Cycloguanil D6 Hydrochloride is a useful tool for pharmacokinetic studies of cycloguanil, a potent anti-malarial drug. The compound is effective against both chloroquine-resistant and chloroquine-sensitive strains of Plasmodium falciparum and is well-tolerated by patients.
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