Indomethacin D7

Product Name Indomethacin D7
Alternate Names Indomethacin Stable Isotopes, Stable Isotopes of Indomethacin
CAT No. CS-O-03251
CAS No. 53-86-1 (Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 364.8 g/mol
Mol. For. C19H9D7ClNO4
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Indomethacin
Purity Not less than 90 %
Smileys O=C(C(C([2H])=C1[2H])=C(C([2H])=C1Cl)[2H])N2C(C([2H])=C([2H])C(OC)=C3[2H])=C3C(CC(O)=O)=C2C
Controlled No
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Indomethacin D7 is a labeled form of the nonsteroidal anti-inflammatory drug (NSAID) indomethacin, which is commonly used to reduce pain, inflammation, and fever. The "D7" in the name refers to the deuterium labeling, which is a stable isotope used in mass spectrometry for quantification purposes. Indomethacin works by inhibiting the production of prostaglandins, which are responsible for causing inflammation and pain in the body. It is often used to treat conditions such as rheumatoid arthritis, osteoarthritis, gout, and ankylosing spondylitis. It can also be used to reduce pain and inflammation associated with menstrual cramps, bursitis, and tendonitis. Chemically, indomethacin D7 has a molecular weight of 364.49 g/mol and a molecular formula of C19H14D7ClN2O4. It is a white to off-white crystalline powder with a melting point of 155-162°C. The compound is soluble in chloroform and methanol but has low solubility in water. Indomethacin D7 is primarily used in research settings for pharmacokinetic and pharmacodynamic studies. It allows researchers to accurately measure the concentration of the drug in biological samples and determine its metabolism and excretion pathways. The deuterium labeling also helps to reduce variability in the data generated by mass spectrometry methods, improving the accuracy and reliability of the results.

Related Compounds

Indomethacin 13C6 | Indomethacin-d4 | Indomethacin ethyl ester D4 | Indomethacin Impurity 6 - D3 | O-Desmethyl Indomethacin D4 |

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