Piperaquine D6

Product Name Piperaquine D6
Alternate Names Piperaquine Stable Isotopes, Stable Isotopes of Piperaquine
CAT No. CS-O-03322
CAS No. 1261394-71-1
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 541.55 g/mol
Mol. For. C₂₉H₂₆D₆Cl₂N₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Piperaquine
Purity 95%
Smileys ClC1=CC(N=CC=C2N3CCN(C([2H])([2H])C([2H])([2H])C([2H])([2H])N4CCN(C5=CC=NC6=C5C=CC(Cl)=C6)CC4)CC3)=C2C=C1
Canonical Smiles C1CN(CCN1CCCN2CCN(CC2)C3=C4C=CC(=CC4=NC=C3)Cl)C5=C6C=CC(=CC6=NC=C5)Cl
InchIKey UCRHFBCYFMIWHC-QLFBILJTSA-N
Inchl InChI=1S/C29H32Cl2N6/c30-22-2-4-24-26(20-22)32-8-6-28(24)36-16-12-34(13-17-36)10-1-11-35-14-18-37(19-15-35)29-7-9-33-27-21-23(31)3-5-25(27)29/h2-9,20-21H,1,10-19H2/i1D2,10D2,11D2
IUPAC 7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]-1,1,2,2,3,3-hexadeuteriopropyl]piperazin-1-yl]quinoline
Controlled No
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Piperaquine D6 is a deuterated version of Piperaquine, an antimalarial drug used to treat and prevent malaria. It is a member of the 4-aminoquinoline family of drugs and is used in combination with other drugs, such as dihydroartemisinin, to treat uncomplicated malaria caused by Plasmodium falciparum. Piperaquine D6 is available in tablet form and is typically taken orally once a day for three days in combination with other antimalarial drugs. It works by interfering with the metabolism of the parasite, preventing it from replicating and causing illness. Chemically, Piperaquine D6 is a bisquinoline compound with a molecular formula of C29H28D6N3, and a molecular weight of 465.64 g/mol. Its pharmacological properties are similar to those of the non-deuterated form of Piperaquine, but its use can offer certain advantages in terms of pharmacokinetics and pharmacodynamics. Piperaquine D6 is generally well-tolerated but can cause side effects such as nausea, vomiting, and diarrhea. It is not recommended for use in pregnant women or children under the age of 2 years. In conclusion, Piperaquine D6 is an effective antimalarial drug used to treat and prevent malaria. Its deuterated form can offer certain advantages in terms of its pharmacokinetics and pharmacodynamics, but it is important to use it under the guidance of a healthcare professional to ensure its safe and effective use.

Related Compounds

Piperaquine-d6 N-Oxide |

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