Allopurinol 13C 15N2

Allopurinol 13C 15N2 is a stable isotope-labeled form of the medication allopurinol, used for the treatment of gout and hyperuricemia. Gout is a type of arthritis caused by the buildup of uric acid crystals in the joints, leading to inflammation and pain. Allopurinol works by inhibiting the enzyme xanthine oxidase, which is responsible for the production of uric acid. The stable isotope labeling of allopurinol 13C 15N2 provides a unique tool for pharmacokinetic and pharmacodynamic studies of this medication. Stable isotopes are non-radioactive isotopes of an element that have a different number of neutrons in the nucleus, allowing for the tracking and quantification of the drug in biological samples. This labeling technique enables researchers to accurately measure the absorption, distribution, metabolism, and excretion of the drug, as well as its effects on the body. Chemically, allopurinol 13C 15N2 contains 13 carbon atoms and 2 nitrogen atoms that are stable isotopes, while the remaining atoms are the same as the non-labeled allopurinol. This labeling does not alter the pharmacological properties of the medication, but it provides a valuable tool for research and drug development. In conclusion, Allopurinol 13C 15N2 is a stable isotope-labeled form of allopurinol, used for the treatment of gout and hyperuricemia. This labeling technique allows for accurate tracking and quantification of the drug in biological samples, providing valuable information for pharmacokinetic and pharmacodynamic studies.