Albendazole D3 (OMe-D3)

Albendazole D3, also known as albendazole-2H3, is a deuterated version of the broad-spectrum anthelmintic drug Albendazole. Albendazole D3 is a white to off-white crystalline powder that is slightly soluble in water and soluble in alcohol, acetone, and chloroform. The deuterated version of Albendazole is primarily used for pharmacokinetic studies, drug metabolism research, and other clinical applications that require isotopically labeled compounds. Albendazole D3 is a benzimidazole derivative that exhibits antiparasitic activity against a range of helminths, including roundworms, tapeworms, and flukes. The drug works by inhibiting the formation of microtubules in the parasite cells, preventing their reproduction and eventually leading to their death. Albendazole D3 is commonly used to treat parasitic infections such as hydatid disease, neurocysticercosis, and ascariasis. Albendazole D3 is generally administered orally, with the dose and duration of treatment depending on the type and severity of the infection. The drug has a half-life of approximately 8 hours and is primarily metabolized in the liver. The major metabolites of Albendazole D3 include albendazole sulfoxide and albendazole sulfone, which are also active against parasites. In conclusion, Albendazole D3 is a valuable tool for research purposes, particularly in understanding the pharmacokinetics and metabolism of Albendazole. Its antiparasitic properties make it an effective treatment for a variety of parasitic infections, improving the quality of life for those affected by these diseases.