Zofenoprilat D5

Product Name Zofenoprilat D5
Alternate Names Zofenopril Stable Isotopes, Stable Isotopes of Zofenopril
CAT No. CS-O-03386
CAS No. 1217716-12-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 330.48 g/mol
Mol. For. C₁₅H₁₄D₅NO₃S₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Zofenopril
Smileys O=C(N(C[C@@H](SC(C([2H])=C1[2H])=C(C([2H])=C1[2H])[2H])C2)[C@@H]2C(O)=O)[C@H](C)CS
Canonical Smiles CC(CS)C(=O)N1CC(CC1C(=O)O)SC2=CC=CC=C2
InchIKey UQWLOWFDKAFKAP-QBORCZMVSA-N
Inchl InChI=1S/C15H19NO3S2/c1-10(9-20)14(17)16-8-12(7-13(16)15(18)19)21-11-5-3-2-4-6-11/h2-6,10,12-13,20H,7-9H2,1H3,(H,18,19)/t10-,12+,13+/m1/s1/i2D,3D,4D,5D,6D
IUPAC (2S,4S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]-4-(2,3,4,5,6-pentadeuteriophenyl)sulfanylpyrrolidine-2-carboxylic acid
Controlled No
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Zofenoprilat D5 is a deuterated form of Zofenoprilat, which is a potent angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension. The deuterated form of Zofenoprilat is used in clinical studies as an internal standard for quantification of Zofenoprilat in human plasma and urine samples. Zofenoprilat D5 has a molecular formula of C12H6D5N2O3S2 and a molecular weight of 319.43 g/mol. It is a white to off-white powder that is soluble in water and methanol but insoluble in organic solvents like ethyl acetate and chloroform. Zofenoprilat D5 is stable under normal laboratory conditions and has a shelf life of at least two years if stored properly. The mechanism of action of Zofenoprilat D5 is similar to that of Zofenoprilat. It inhibits the activity of ACE, an enzyme that converts angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting ACE, Zofenoprilat D5 reduces the production of angiotensin II, leading to vasodilation and decreased blood pressure. In conclusion, Zofenoprilat D5 is a useful tool for quantification of Zofenoprilat in clinical studies. Its chemical and physical properties make it a stable and reliable internal standard for the analysis of Zofenoprilat in biological samples.

Related Compounds

Zofenoprilat-NES-d5 | Zofenoprilat-d5 N-Ethyl Succinimide | Zofenopril D5 |

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