Pantoprazole D8

Product Name Pantoprazole D8
Alternate Names Pantoprazole Stable Isotopes, Stable Isotopes of Pantoprazole
CAT No. CS-O-03598
CAS No. 934294-34-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 391.42 g/mol
Mol. For. C₁₆H₇D₈F₂N₃O₄S
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Pantoprazole
Purity 98.86
Therapeutic Anti ulcer
Smileys O=[S](C1=NC2=CC(OC(F)F)=CC=C2N1)CC(N=C3[2H])=C(C(OC([2H])([2H])[2H])=C3[2H])OC([2H])([2H])[2H]
Controlled No
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Pantoprazole D8 is a deuterated derivative of Pantoprazole, which is a proton pump inhibitor used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. It works by inhibiting the proton pump, which is responsible for the secretion of acid in the stomach. Pantoprazole D8 is a stable isotope-labeled compound that is used as a reference standard in pharmacokinetic and metabolic studies. Deuterium is a non-radioactive isotope of hydrogen, which has a higher mass than the hydrogen atom. The substitution of hydrogen with deuterium in Pantoprazole D8 provides a unique chemical signature that can be used to track the fate of the drug in vivo. The chemical formula of Pantoprazole D8 is C16H14D8N3O2S, and its molecular weight is 369.49 g/mol. The compound is a white to off-white crystalline powder that is soluble in water and methanol. Pantoprazole D8 is administered orally in the form of delayed-release tablets. The recommended dose for adults is 40 mg once daily for up to 8 weeks. The drug should be taken before a meal, and the tablet should not be crushed or chewed. Pantoprazole D8 is metabolized in the liver and excreted in the urine and feces. The elimination half-life of the drug is approximately 1 hour, and the clearance rate is 7-10 L/h. The drug is primarily metabolized by the cytochrome P450 enzyme system, specifically CYP2C19 and CYP3A4. Patients with impaired liver function may require a lower dose of the drug.

Related Compounds

Pantoprazole D3 | Pantoprazole sulphide-d6 | Pantoprazole-D4 | Pantoprazole Sulfide-D7 (Major) | Pantoprazole-d5 Sulfone (Major) | Pantoprazole D6 | Pantoprazole Sulfone-d6 | Pantoprazole D7 | O-Desmethyl Pantoprazole O-Sulfate D3 |

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