Trandolaprilat D5

Product Name Trandolaprilat D5
Alternate Names Trandolapril Stable Isotopes, Stable Isotopes of Trandolapril
CAT No. CS-O-03609
CAS No. 1356841-27-4
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 407.51 g/mol
Mol. For. C₂₂H₂₅D₅N₂O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Trandolapril
Purity Not less than 90 %
Therapeutic Anti-Hypertensives
Smileys CC(C(=O)N1C2CCCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
Canonical Smiles CC(C(=O)N1C2CCCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
InchIKey AHYHTSYNOHNUSH-PPEBBQNBSA-N
Inchl InChI=1S/C22H30N2O5/c1-14(23-17(21(26)27)12-11-15-7-3-2-4-8-15)20(25)24-18-10-6-5-9-16(18)13-19(24)22(28)29/h2-4,7-8,14,16-19,23H,5-6,9-13H2,1H3,(H,26,27)(H,28,29)/t14-,16+,17-,18-,19-/m0/s1/i2D,3D,4D,7D,8D
IUPAC (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-(2,3,4,5,6-pentadeuteriophenyl)propyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
Controlled No
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Trandolaprilat D5 is a deuterated form of Trandolaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension and heart failure. It works by inhibiting the conversion of angiotensin I to angiotensin II, thereby preventing blood vessel constriction and reducing blood pressure. Trandolaprilat D5 is typically used in clinical research studies to determine the pharmacokinetic properties of Trandolaprilat, as deuterium labeling provides a unique way to track and measure drug metabolism and distribution in the body. The use of Trandolaprilat D5 allows researchers to accurately quantify the concentration and distribution of Trandolaprilat in the body, which can help to optimize dosing and minimize potential side effects. From a chemical perspective, Trandolaprilat D5 is a stable isotope-labeled compound, where deuterium atoms are substituted for hydrogen atoms in the molecular structure. This modification allows for the detection and quantification of Trandolaprilat D5 in biological samples using mass spectrometry, which is a powerful analytical tool used in drug discovery and development. In conclusion, Trandolaprilat D5 is a valuable research tool that provides insights into the pharmacokinetic properties of Trandolaprilat. Its use in clinical studies can improve dosing accuracy and minimize potential side effects, ultimately leading to better patient outcomes.

Related Compounds

Trandolapril D5 | Trandolapril D6 | Trandolaprilat D6 |

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