Fidaxomicin D7
| Product Name | Fidaxomicin D7 |
|---|---|
| Alternate Names | Fidaxomicin Stable Isotopes, Stable Isotopes of Fidaxomicin |
| CAT No. | CS-O-03624 |
| CAS No. | 2143934-06-7 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 1065.08 g/mol |
| Mol. For. | C₅₂H₆₇D₇Cl₂O₁₈ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Fidaxomicin |
| Purity | 95% |
| Therapeutic | Antibiotics |
| Smileys | O=C(C(C(O)=C(Cl)C(O)=C1Cl)=C1CC)O[C@H]([C@H](O[C@H]2OC/C(C(O[C@](C/C=C3C)([H])[C@H](O)C)=O)=C\C=C\C[C@](/C(C)=C\[C@H](CC)[C@@H](O[C@](OC(C)(C)[C@H](OC(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)[C@H]4O)([H])[C@@H]4O)\C(C)=C/3)([H])O)C)[C@@H]([C@@H]2OC匀䰀 |
| Canonical Smiles | CCC1C=C(C(CC=CC=C(C(=O)OC(CC=C(C=C(C1OC2C(C(C(C(O2)(C)C)OC(=O)C(C)C)O)O)C)C)C(C)O)COC3C(C(C(C(O3)C)OC(=O)C4=C(C(=C(C(=C4O)Cl)O)Cl)CC)O)OC)O)C |
| InchIKey | ZVGNESXIJDCBKN-UUEYKCAUSA-N |
| Inchl | InChI=1S/C52H74Cl2O18/c1-13-30-22-26(6)33(56)18-16-15-17-31(23-66-51-45(65-12)42(61)44(29(9)67-51)69-49(64)35-32(14-2)36(53)39(58)37(54)38(35)57)48(63)68-34(28(8)55)20-19-25(5)21-27(7)43(30)70-50-41(60)40(59)46(52(10,11)72-50)71-47(62)24(3)4/h15-17,19,21-22,24,28-30,33-34,40-46,50-51,55-61H,13-14,18,20,23H2,1-12H3/b16-15+,25-19+,26-22+,27-21+,31-17+/t28-,29-,30+,33+,34+,40-,41+,42+,43+,44-,45+,46+,50-,51-/m1/s1 |
| IUPAC | [(2R,3S,4S,5S,6R)-6-[[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl-5-(2-methylpropanoyloxy)oxan-2-yl]oxy-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxo-1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy]-4-hydroxy-5-methoxy-2-methyloxan-3-yl] 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Fidaxomicin D7 is a derivative of the antibiotic Fidaxomicin, which is used for the treatment of Clostridium difficile-associated diarrhea (CDAD). It is a macrocyclic antibiotic that selectively targets the RNA polymerase of C. difficile, which is responsible for the replication of the bacterium. Fidaxomicin D7 is a deuterated form of Fidaxomicin, which means that seven of its hydrogen atoms have been replaced by deuterium atoms. This modification enhances the drug's stability and prolongs its half-life, allowing for less frequent dosing.
The chemical structure of Fidaxomicin D7 consists of a macrocycle with a unique spiroketal moiety, which is responsible for its potent antibacterial activity. The drug is administered orally and is rapidly absorbed in the intestine. It is metabolized in the liver and excreted primarily in the feces, with a small portion being eliminated in the urine.
Fidaxomicin D7 is highly effective in the treatment of CDAD, with a cure rate of up to 90%. It has also been shown to have a lower rate of recurrence compared to other antibiotics used for CDAD. However, it is important to note that Fidaxomicin D7 is a prescription-only drug and should only be used under the guidance of a healthcare professional. Additionally, it is important to follow the prescribed dosing regimen and complete the full course of treatment to ensure maximum effectiveness and minimize the development of antibiotic resistance.
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Related Compounds
Fidaxomicin metabolite OP-1118 D5 |