Nebivolol Impurity A

Product Name Nebivolol Impurity A
Alternate Names Nebivolol Impurities, Impurities of Nebivolol
CAT No. CS-O-05763
CAS No. 118457-16-2
Category Impurities
Stock IN-Stock
Mol. Wt. 405.44 g/mol
Mol. For. C₂₂H₂₅F₂NO₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nebivolol
Purity 95%
Smileys O[C@H]([C@@]1([H])OC2=CC=C(F)C=C2CC1)CNC[C@@H]([C@]3([H])OC4=CC=C(F)C=C4CC3)O
Canonical Smiles C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O
InchIKey KOHIRBRYDXPAMZ-YHDSQAASSA-N
Inchl InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2/t17-,18-,21-,22+/m0/s1
IUPAC (1S)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol
Controlled No
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Nebivolol Impurity A is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for the analysis and testing of nebivolol, a beta-blocker medication used to treat high blood pressure and other cardiovascular conditions. This impurity is a minor component of nebivolol drug substance and is often present in trace amounts. Chemically, Nebivolol Impurity A is known as (1RS,2RS)-1-(6-methoxyquinolin-4-yl)-2-(3-methylphenyl)ethanol. It has a molecular weight of 315.4 g/mol and a molecular formula of C20H21NO2. It is a white to off-white crystalline powder that is soluble in methanol, ethanol, and acetonitrile. The usage of Nebivolol Impurity A in the pharmaceutical industry is primarily for analytical purposes. It is used as a reference standard in the development and validation of analytical methods for the quantification of nebivolol in drug products. Additionally, it is used to identify and characterize the impurities present in nebivolol drug substance and drug products. In conclusion, Nebivolol Impurity A is an important reference standard in the pharmaceutical industry for the analysis and testing of nebivolol drug substance and drug products. Its usage in the development and validation of analytical methods ensures the quality and safety of nebivolol medications.

Related Compounds

Nebivolol Impurity (RRSR+RSRR) | Nebivolol Impurity 2 HCl (SR,RS) | Nebivolol Related compound A (RSSR+SRRS) | N-Nitroso Nebivolol | Nebivolol Impurity 10 (RS,SR) | Nebivolol impurity 1 | Nebivolol isomers - RSRR | Nebivolol Impurity 8 (SR) | Nebivolol Impurity 3 | Nebivolol EP Impurity D | Nebivolol Isomer (SRSR+RSRS) | Nebivolol lactose adduct | Nebivolol Impurity 20 (SS,SS) | Nebivolol Impurity 34 (RSRR+RRRR) | Nebivolol Impurity 14 | Nebivolol Impurity B (SR,SS) | Nebivolol Impurity 13 (SS,SS) | Defluoro Nebivolol | N-Benzyl (-)-Nebivolol | Nebivolol Hydrochloride At RRT 0.88 | Nebivolol Impurity 26 | Nebivolol Impurity 6 (SS) | Nebivolol Impurity 12 (RR,RR) | Nebivolol Impurity 7 (RR) | Nebivolol Impurity 12 | Nebivolol Impurity 11 (SR,SR) | Nebivolol Impurity 5 | Nebivolol Impurity 9 (RS) | Nebivolol RRRS isomer | Didefluoro Nebivolol | Nebivolol Impurity 17 (RS,SR) | Nebivolol isomers (RSRS+RSSR+SRRS) | Nebivolol Impurity 4 | Nebivolol Hydrochloride At RRT 1.13 | Nebivolol Impurity (RSRR+SRSS) | Nebivolol Stereoisomer Mixture | Defluoro Nebivolol (Mixture of Diastereomers) | Nebivolol Impurity 1 (RR,SS) | N-Nitroso Nebivolol (Mixture of Diastereomers) | Nebivolol RSSS Isomer | Nebivolol Impurity (SSRS+SRSS) | rel-Desfluoro Nebivolol Impurity | Nebivolol HCL unwanted isomer Impurity | Nebivolol Impurity 3 (RRSS) (HCl) | rel-N-Benzyl Nebivolol |

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