10 hydroxy Camptothecin
| Product Name | 10 hydroxy Camptothecin |
|---|---|
| Alternate Names | Camptothecin Impurities, Impurities of Camptothecin |
| CAT No. | CS-O-06296 |
| CAS No. | 19685-09-7 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 364.4 g/mol |
| Mol. For. | C20H16N2O5 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Camptothecin |
| Purity | >98% |
| Smileys | CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O |
| Canonical Smiles | CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O |
| InchIKey | HAWSQZCWOQZXHI-FQEVSTJZSA-N |
| Inchl | InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1 |
| IUPAC | (19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
10-hydroxy camptothecin (10-HCPT) is a natural product derived from the bark of the Chinese tree Camptotheca acuminate. It is a potent alkaloid that has shown promise in the treatment of various cancers, including lung, breast, and ovarian cancers. 10-HCPT works by inhibiting topoisomerase I, an enzyme that is essential for DNA replication and repair. By preventing this enzyme from functioning, 10-HCPT causes DNA damage and triggers apoptosis (cell death) in cancer cells.
In addition to its anti-cancer properties, 10-HCPT has also been studied for its potential in treating viral infections, such as hepatitis B and HIV. Preliminary studies have shown that 10-HCPT can inhibit viral replication and reduce the viral load in infected cells.
Chemically, 10-HCPT is a yellow crystalline solid with a molecular weight of 389.42 g/mol. It is soluble in organic solvents such as DMSO and ethanol, but insoluble in water. The compound has a melting point of 278-280°C and a boiling point of 682.3°C at 760 mmHg.
Overall, 10-hydroxy camptothecin is a promising compound that has shown efficacy in the treatment of cancer and viral infections. However, further research is needed to fully understand its potential and to optimize its use in clinical settings.
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Related Compounds
Camptothecin 7-Ethyl Impurity | Camptothecin Impurity D | keto protection of Camptothecin impurity | Camptothecin Impurity 8 |