5-Chloro-8-hydroxyquinoline

Product Name 5-Chloro-8-hydroxyquinoline
Alternate Names Quinoline Impurities, Impurities of Quinoline
CAT No. CS-O-06307
CAS No. 130-16-5
Category Impurities
Stock IN-Stock
Mol. Wt. 179.60 g/mol
Mol. For. C₉H₆ClNO
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Quinoline
Purity 95%
Smileys ClC1=C(C=CC=N2)C2=C(O)C=C1
Canonical Smiles C1=CC2=C(C=CC(=C2N=C1)O)Cl
InchIKey CTQMJYWDVABFRZ-UHFFFAOYSA-N
Inchl InChI=1S/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H
IUPAC 5-chloroquinolin-8-ol
Controlled No
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5-Chloro-8-hydroxyquinoline, also known as 5-Cl-8-OHQ, is a chemical compound that is commonly used in a variety of applications. This compound is an organic molecule that contains a chlorine atom and a hydroxy group attached to a quinoline ring system. It is a yellow powder that is soluble in organic solvents and slightly soluble in water. One of the primary uses of 5-Cl-8-OHQ is as an intermediate in the production of pharmaceuticals. It is commonly used in the synthesis of antimalarial drugs, such as chloroquine and amodiaquine. Additionally, it is used in the production of anti-inflammatory and antimicrobial agents. The compound has a wide range of biological activities, including antibacterial, antifungal, and antiviral properties. It is believed that the mechanism of action involves the inhibition of nucleic acid synthesis in microorganisms, thus preventing their growth and reproduction. In terms of chemical information, 5-Cl-8-OHQ has a molecular formula of C9H6ClNO and a molecular weight of 183.6 g/mol. The compound has a melting point of 190-192°C and a boiling point of 382°C. It is stable under normal conditions of use and storage, but may react with strong oxidizing agents or reducing agents. Overall, 5-Cl-8-OHQ is a versatile compound with a range of applications in the pharmaceutical and biotechnology industries. Its unique chemical and biological properties make it a valuable tool for researchers and scientists in these fields.

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