Abacavir D4
| Product Name | Abacavir D4 |
|---|---|
| Alternate Names | Abacavir Stable Isotopes, Stable Isotopes of Abacavir |
| CAT No. | CS-O-06371 |
| CAS No. | 1260619-56-4 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 290.36 g/mol |
| Mol. For. | C₁₄H₁₄D₄N₆O |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Abacavir |
| Purity | 95% |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO |
| Canonical Smiles | C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)C4CC(C=C4)CO |
| InchIKey | MCGSCOLBFJQGHM-ZOTQTBSBSA-N |
| Inchl | InChI=1S/C14H18N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19)/t8-,10+/m1/s1/i2D2,3D2 |
| IUPAC | [(1S,4R)-4-[2-amino-6-[(2,2,3,3-tetradeuteriocyclopropyl)amino]purin-9-yl]cyclopent-2-en-1-yl]methanol |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Abacavir D4 is a deuterated analog of Abacavir, an antiretroviral drug used in the treatment of HIV and AIDS. Deuterated compounds are similar to their non-deuterated counterparts, but with the substitution of hydrogen atoms with heavier deuterium atoms, which can provide unique advantages in drug development.
Abacavir D4 is used in combination with other antiretroviral drugs to treat HIV-1 infection in adults and children. It works by inhibiting the activity of the reverse transcriptase enzyme, which is necessary for the replication of the virus. This prevents the virus from multiplying, reducing the amount of virus in the body and slowing down the progression of the disease.
In terms of chemical information, Abacavir D4 has a molecular formula of C14H11D4N5O and a molecular weight of 280.36 g/mol. Its physical properties include a melting point range of 203-208°C and a solubility of 15 mg/mL in water.
Abacavir D4 is generally well-tolerated, with common side effects including headache, fatigue, nausea, and diarrhea. However, in rare cases, it can cause severe allergic reactions, which can be life-threatening. Patients are advised to seek medical attention immediately if they experience symptoms such as fever, rash, or difficulty breathing.
In conclusion, Abacavir D4 is an important antiretroviral drug in the treatment of HIV and AIDS. Its deuterated form offers potential advantages in terms of pharmacokinetics and pharmacodynamics, and it is generally well-tolerated by patients. However, as with all medications, it should be used only under the guidance of a healthcare professional.
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Related Compounds
Abacavir-d4 HCl | trans-Abacavir-d4 Hydrochloride | abacavir D5 | Abacavir-d4 5’-4-Chloro-6-methylpyrimidine-2,5-diamine |