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Abiraterone D4 is a deuterated form of abiraterone, a potent and selective inhibitor of the enzyme CYP17A1, which is involved in the production of androgens such as testosterone. Abiraterone D4 is used in the treatment of metastatic castration-resistant prostate cancer (mCRPC) in adult men who have previously received chemotherapy containing docetaxel and who are now resistant to hormonal therapy.
The chemical formula of Abiraterone D4 is C24H31D4NO, and it has a molecular weight of 365.56 g/mol. It is a white to pale yellow crystalline powder that is practically insoluble in water but soluble in organic solvents such as ethanol and methanol.
Abiraterone D4 works by blocking the production of androgens in the body, which can help slow the progression of prostate cancer. It is typically given in combination with prednisone, a steroid medication that helps reduce inflammation and side effects of abiraterone.
As with any medication, there are potential side effects associated with Abiraterone D4, including fatigue, joint pain, hypertension, cardiac disorders, and liver function abnormalities. Patients should be closely monitored for these and any other side effects that may arise during treatment.
Overall, Abiraterone D4 is an important treatment option for patients with advanced prostate cancer, and its use can help improve outcomes and quality of life in these patients.
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