Rac-Ambrisentan D3
| Chemical Name | Rac-Ambrisentan D3 |
|---|---|
| Alternate Names | Ambrisentan Stable Isotopes, Stable Isotopes of Ambrisentan |
| CAT No. | CS-O-06398 |
| CAS Registry# | 1189479-60-4 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 381.44 g/mol |
| Mol. For. | C22H19D3N2O4 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Ambrisentan |
| Purity | 97.83 |
| Smileys | CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C |
| Canonical Smiles | CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C |
| InchIKey | OUJTZYPIHDYQMC-HPRDVNIFSA-N |
| Inchl | InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/i3D3 |
| IUPAC | 2-(4,6-dimethylpyrimidin-2-yl)oxy-3,3-diphenyl-3-(trideuteriomethoxy)propanoic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Rac-Ambrisentan D3 is a medication used to treat pulmonary arterial hypertension (PAH). It is a derivative of the endothelin receptor antagonist, ambrisentan. It works by blocking the effects of endothelin, a hormone that constricts blood vessels and contributes to the development of PAH.
The chemical structure of Rac-Ambrisentan D3 consists of a pyridine ring, a pyrrolidine ring, and a carboxylic acid group. It is available in the form of a tablet for oral administration.
The recommended starting dose of Rac-Ambrisentan D3 is 5 mg once daily, with or without food. The dose may be increased after four weeks to 10 mg once daily based on the patient's response and tolerability.
Rac-Ambrisentan D3 should not be used in patients with severe liver impairment or in those who are pregnant or breastfeeding. It may also interact with other medications, including cyclosporine and rifampin.
Common side effects of Rac-Ambrisentan D3 include headache, flushing, nasal congestion, and peripheral edema. In rare cases, it may cause liver damage or pulmonary edema.
In conclusion, Rac-Ambrisentan D3 is a medication used to treat PAH by blocking the effects of endothelin. It is available in the form of a tablet for oral administration and should only be used under the supervision of a healthcare professional.
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Related Compounds
rac 4-Hydroxymethyl Ambrisentan-d3 | rac Ambrisentan-d3 Methyl Ester | Ambrisentan D3 | Ambrisentan D10 | Ambrisentan acyl-β-D-glucuronide D10 | rac-Ambrisentan-d5 |