R-Amlodipine D4

R-Amlodipine D4 is a deuterated form of the calcium channel blocker R-amlodipine. It is used to treat hypertension and angina, by relaxing blood vessels and improving blood flow. R-amlodipine D4 is a dihydropyridine calcium channel blocker that selectively inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle. This results in vasodilation of the peripheral arterioles and reduces the workload on the heart, which can help to lower blood pressure and reduce the frequency and severity of angina attacks. The deuterium substitution in R-Amlodipine D4 provides several benefits. Firstly, it increases the half-life of the drug, meaning that it can remain in the body for longer periods of time, providing a sustained effect. Additionally, deuterated drugs have been shown to have increased metabolic stability, which can reduce the risk of toxicity and side effects. R-amlodipine D4 is typically administered orally, with the dosage prescribed by a healthcare professional depending on the individual patient's needs and medical history. It is important to follow the prescribed dosage and not exceed the recommended amount, as this can increase the risk of side effects such as dizziness, headaches, and swelling of the ankles. Overall, R-Amlodipine D4 is a widely used calcium channel blocker that can help to manage hypertension and angina. Its deuterium substitution provides increased stability and a longer half-life, allowing for a sustained therapeutic effect.