Chemical Name |
S-Amlodipine D4 |
Alternate Names |
Amlodipine Stable Isotopes, Stable Isotopes of Amlodipine |
CAT No. |
CS-O-06405
|
CAS Registry# |
1346617-19-3 |
Category |
Stable Isotopes |
Stock |
Enquire
|
Mol. Wt. |
412.90 g/mol |
Mol. For. |
C₂₀H₂₁D₄ClN₂O₅
|
Hazardous |
This is a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Amlodipine |
Purity |
95% |
Therapeutic |
Anti-Cancer / Oncology |
Smileys |
O=C(C([C@@H](C(C=CC=C1)=C1Cl)C(C(OC)=O)=C(C)N2)=C2COC([2H])([2H])C([2H])([2H])N)OCC |
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
Return |
Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
Ordering |
Place your order online or by email sales@clearsynth.com |
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S-Amlodipine D4 is a deuterated version of S-amlodipine, a calcium channel blocker used to treat high blood pressure and chest pain caused by angina. The deuterium substitution at the four positions of the molecule enhances its stability and efficacy, leading to a longer half-life and improved pharmacokinetic properties.
The mechanism of action of S-amlodipine D4 involves the inhibition of L-type calcium channels in the smooth muscle cells of the blood vessels, leading to relaxation and vasodilation. This results in the reduction of blood pressure and the improvement of blood flow to the heart, reducing the risk of heart attack and stroke.
S-amlodipine D4 is typically administered orally in the form of a tablet, with a recommended dosage of 5 to 10 mg per day. It is important to follow the instructions provided by a healthcare professional and to not exceed the recommended dose.
The chemical formula of S-amlodipine D4 is C20H23D4ClN2O5, with a molecular weight of 422.97 g/mol. It belongs to the dihydropyridine class of calcium channel blockers and is a white to off-white crystalline powder. S-amlodipine D4 is stable under normal conditions and is compatible with a range of excipients used in pharmaceutical formulations.
Overall, S-amlodipine D4 is a highly effective and safe medication for the treatment of hypertension and angina, with improved pharmacokinetic properties due to its deuterium substitution.