Artemether 13C D3
| Product Name | Artemether 13C D3 |
|---|---|
| Alternate Names | Artemether Stable Isotopes, Stable Isotopes of Artemether |
| CAT No. | CS-O-06415 |
| CAS No. | 71963-77-4Unlabeled |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 302.39 g/mol |
| Mol. For. | C₁₅¹³CH₂₃D₃O₅ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Artemether |
| Purity | 98.02 |
| Smileys | C[C@@H]1[C@@](CC[C@@H](C)[C@]2([H])CC[C@]3(C)O4)([H])[C@@]2(OO3)[C@]4([H])O[C@@H]1O[13C]([2H])([2H])[2H] |
| Canonical Smiles | CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC)C |
| InchIKey | SXYIRMFQILZOAM-HVNFFKDJSA-N |
| Inchl | InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1 |
| IUPAC | (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Artemether 13C D3 is a deuterated form of the antimalarial drug Artemether. It is a synthetic derivative of artemisinin, a plant-based compound extracted from the Chinese herb Artemisia annua. Artemether 13C D3 is used in the treatment of uncomplicated malaria caused by the Plasmodium falciparum parasite, which is responsible for the most severe form of the disease. It is typically administered in combination with other antimalarial drugs, such as lumefantrine.
The deuterium substitution in Artemether 13C D3 allows for more accurate studies of the drug's pharmacokinetics, as it can be easily distinguished from the non-deuterated form in tests and analyses. This information can be used to optimize dosing strategies and improve treatment outcomes.
Artemether 13C D3 is metabolized in the liver by enzymes known as cytochrome P450s, specifically CYP2B6 and CYP3A4. These enzymes convert the drug into its active form, dihydroartemisinin, which acts by targeting and destroying the malaria parasite within the red blood cells.
Overall, Artemether 13C D3 is an important tool in the fight against malaria, providing valuable insights into the pharmacokinetics and metabolism of artemether and helping to improve treatment strategies for this deadly disease.
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Related Compounds
Artemether D3 |