Benazeprilat D5
| Product Name | Benazeprilat D5 |
|---|---|
| Alternate Names | Benazepril Stable Isotopes, Stable Isotopes of Benazepril |
| CAT No. | CS-O-06436 |
| CAS No. | 1279033-05-4 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 401.47 g/mol |
| Mol. For. | C₂₂H₁₉D₅N₂O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Benazepril |
| Purity | Not less than 90 % |
| Therapeutic | Anti-Hypertensives |
| Smileys | OC(CN1C2=CC=CC=C2CC[C@H](N[C@H](C(O)=O)CCC(C([2H])=C3[2H])=C(C([2H])=C3[2H])[2H])C1=O)=O |
| Canonical Smiles | C1CC2=CC=CC=C2N(C(=O)C1NC(CCC3=CC=CC=C3)C(=O)O)CC(=O)O |
| InchIKey | MADRIHWFJGRSBP-IARVFAGTSA-N |
| Inchl | InChI=1S/C22H24N2O5/c25-20(26)14-24-19-9-5-4-8-16(19)11-13-17(21(24)27)23-18(22(28)29)12-10-15-6-2-1-3-7-15/h1-9,17-18,23H,10-14H2,(H,25,26)(H,28,29)/t17-,18-/m0/s1/i1D,2D,3D,6D,7D |
| IUPAC | (2S)-2-[[(3S)-1-(carboxymethyl)-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl]amino]-4-(2,3,4,5,6-pentadeuteriophenyl)butanoic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Benazeprilat D5 is a deuterated form of Benazeprilat, a medication used to treat hypertension and heart failure. The deuterated form is used primarily for research and development purposes, such as in clinical trials, to help identify the metabolic pathways of the drug and determine its efficacy.
Benazeprilat D5 is a competitive inhibitor of angiotensin-converting enzyme (ACE), which plays a role in the regulation of blood pressure. By inhibiting ACE, Benazeprilat D5 decreases the production of Angiotensin II, a hormone that causes blood vessels to constrict, leading to increased blood pressure. In addition, Benazeprilat D5 also increases the levels of bradykinin, which is a vasodilator and helps to lower blood pressure.
The chemical formula for Benazeprilat D5 is C24H28D5N3O5, with a molecular weight of 444.6 g/mol. It is administered orally, with a recommended dose of 10 mg once daily for hypertension and 20 mg once daily for heart failure. The half-life of Benazeprilat D5 is approximately 10-11 hours, with peak plasma concentrations reached within 1-2 hours after administration.
Overall, Benazeprilat D5 is an important tool in the research and development of new antihypertensive medications, helping to improve our understanding of the metabolic pathways and efficacy of this class of drugs.
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Related Compounds
Benazepril D5 | N-Nitroso Benazepril D5 |