Canrenone D7

Product Name Canrenone D7
Alternate Names Canrenone Stable Isotopes, Stable Isotopes of Canrenone
CAT No. CS-O-06459
CAS No. 976-71-6(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 347.50 g/mol
Mol. For. C₂₂H₂₁D₇O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Canrenone
Purity 95%
Smileys C[C@@]12[C@](OC3=O)(CC3([2H])[2H])CC[C@@]1([H])[C@@](C([2H])=CC4=C([2H])C5=O)([2H])[C@]([C@]4(CC5([2H])[2H])C)([H])CC2
Canonical Smiles CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC45CCC(=O)O5)C
InchIKey UJVLDDZCTMKXJK-WNHSNXHDSA-N
Inchl InChI=1S/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/m1/s1
IUPAC (8R,9S,10R,13S,14S,17R)-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
Controlled No
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Canrenone D7 is a deuterated analog of Canrenone, which is a potent and selective antagonist of the mineralocorticoid receptor. Canrenone D7 is primarily used in scientific research related to the treatment of cardiovascular diseases such as hypertension, heart failure, and edema. Chemically, Canrenone D7 is a derivative of Spironolactone, which is a diuretic and aldosterone antagonist. The deuterated form of Canrenone is created by replacing some of the hydrogen atoms with deuterium atoms. This modification increases the molecular weight of Canrenone D7 and makes it more stable and resistant to metabolic degradation in the body. In terms of usage, Canrenone D7 is predominantly used in drug metabolism and pharmacokinetic studies, where it is used as an internal standard in the analysis of Canrenone and its metabolites. It is also used in clinical studies to determine the pharmacokinetic parameters of Canrenone in humans. In conclusion, Canrenone D7 is a useful tool for researchers interested in studying the pharmacokinetics and metabolism of Canrenone. Its chemical properties and stability make it an ideal internal standard for analytical purposes, and its use in clinical studies helps to provide valuable information on the safety and efficacy of Canrenone in human patients.

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