Cevimeline D4 hydrochloride

Product Name Cevimeline D4 hydrochloride
Alternate Names Cevimeline Stable Isotopes, Stable Isotopes of Cevimeline
CAT No. CS-O-06478
CAS No. 107220-28-0(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 239.80 g/mol
Mol. For. C₁₀H₁₄D₄ClNOS
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Cevimeline
Smileys [2H][C@]1(O[C@@]2(C(CC3)CCN3C2)CS1)C([2H])([2H])[2H].Cl
Canonical Smiles CC1OC2(CN3CCC2CC3)CS1.Cl
InchIKey SURWTGAXEIEOGY-GHXDPTCOSA-N
Inchl InChI=1S/C10H17NOS.ClH/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;/h8-9H,2-7H2,1H3;1H/t8-,10-;/m1./s1
IUPAC (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane];hydrochloride
Controlled No
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Cevimeline D4 hydrochloride is a medication that is used to treat symptoms associated with dry mouth caused by Sjögren's syndrome. It is a cholinergic agonist that works by stimulating the production of saliva. Cevimeline D4 hydrochloride is typically administered orally in the form of a capsule or tablet. Chemically, Cevimeline D4 hydrochloride is a selective muscarinic M1 and M3 receptor agonist. It has a molecular formula of C10H18D4ClN2O2 and a molecular weight of 232.73 g/mol. Its chemical structure is similar to acetylcholine, a neurotransmitter that plays a key role in the parasympathetic nervous system. Cevimeline D4 hydrochloride is metabolized in the liver and excreted through the kidneys. It has a half-life of approximately 2-3 hours. It is important to note that Cevimeline D4 hydrochloride may interact with other medications, including anticholinergic drugs, and should be used with caution in patients with certain medical conditions, such as asthma, gastrointestinal obstruction, or urinary tract obstruction. In clinical trials, Cevimeline D4 hydrochloride has been shown to significantly improve symptoms of dry mouth in patients with Sjögren's syndrome. Common side effects of Cevimeline D4 hydrochloride include sweating, nausea, diarrhea, and headaches.

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