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Diphenhydramine D5 Hydrochloride

Chemical Name Diphenhydramine D5 Hydrochloride
CAT No. CS-O-06550
CAS Registry# 1219795-16-0
Status Prompt Dispatch
Category Stable Isotopes
Mol. Wt. 260.4 : 36.5 g/mol
Mol. For. C17H16D5NO : HCl
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information

Controlled No
Parent API Diphenhydramine
Purity 99.52
Therapeutic Antihistamine
Smileys CN(C)CCOC(C1=CC=CC=C1)C(C([2H])=C2[2H])=C(C([2H])=C2[2H])[2H].Cl
Canonical Smiles CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Inchl InChI=1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H/i1D2,2D3;
IUPAC 2-benzhydryloxy-N-(dideuteriomethyl)-N-(trideuteriomethyl)ethanamine;hydrochloride
Hazardous Yes

Usage and description

Diphenhydramine D5 Hydrochloride is a medication used to treat allergies, insomnia, and motion sickness. It is a derivative of diphenhydramine, an antihistamine drug that inhibits the action of histamine in the body. Diphenhydramine D5 Hydrochloride is a deuterated form of diphenhydramine, meaning that it contains five deuterium atoms instead of hydrogen atoms. This modification makes it useful in pharmacokinetic studies, as it allows researchers to track the drug's distribution and metabolism in the body. The chemical formula of Diphenhydramine D5 Hydrochloride is C17H21D5NO•HCl, with a molecular weight of 306.87 g/mol. It is a white, crystalline powder that is soluble in water and ethanol. The drug works by blocking the H1 histamine receptors in the body, which reduces the symptoms of allergies and promotes sleep. Diphenhydramine D5 Hydrochloride is usually taken orally, either as a tablet or a liquid. The recommended dosage varies depending on the condition being treated and the patient's age and weight. Side effects of the drug can include drowsiness, dizziness, dry mouth, and blurred vision. In rare cases, Diphenhydramine D5 Hydrochloride can cause more serious side effects such as seizures or anaphylaxis. Overall, Diphenhydramine D5 Hydrochloride is a useful medication for treating allergies and promoting sleep. Its deuterated form allows researchers to better understand its pharmacokinetics, which could lead to improved treatments in the future.

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