Hydrochlorothiazide 15N2 13C D2

Hydrochlorothiazide 15N2 13C D2 (HCTZ) is a medication used to treat high blood pressure and fluid retention in the body. It belongs to the thiazide diuretic class of drugs, which work by increasing the amount of salt and water that is excreted in the urine. Chemically, HCTZ is composed of hydrogen, carbon, nitrogen, chlorine, and deuterium atoms. The presence of 15N2, 13C, and D2 isotopes in the molecule indicates that it has been synthesized using stable isotope labeling techniques, which can be useful for research purposes. HCTZ is typically taken orally in tablet form, and its effects can be felt within a few hours of ingestion. It works by blocking the reabsorption of sodium and chloride ions in the kidneys, which leads to increased excretion of water and salts from the body. This helps to lower blood pressure and reduce swelling caused by excess fluid buildup. While HCTZ is generally considered safe and effective for most people, it can cause side effects such as dizziness, headaches, nausea, and electrolyte imbalances. It may also interact with other medications, so it is important to consult with a healthcare provider before taking HCTZ or any other medication. Overall, HCTZ is a useful medication for managing hypertension and edema, and its stable isotope labeling can provide insights into its pharmacokinetics and metabolism.