N-Desmethyl Imatinib D8
| Product Name | N-Desmethyl Imatinib D8 |
|---|---|
| Alternate Names | Imatinib Stable Isotopes, Stable Isotopes of Imatinib |
| CAT No. | CS-O-06677 |
| CAS No. | 1185103-28-9 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 487.63 g/mol |
| Mol. For. | C₂₈H₂₁D₈N₇O |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Imatinib |
| Purity | 99.29 |
| Canonical Smiles | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCNCC3)NC4=NC=CC(=N4)C5=CN=CC=C5 |
| InchIKey | BQQYXPHRXIZMDM-DBVREXLBSA-N |
| Inchl | InChI=1S/C28H29N7O/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34)/i13D2,14D2,15D2,16D2 |
| IUPAC | N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)methyl]benzamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Desmethyl Imatinib D8 is a deuterated form of N-desmethyl imatinib, which is a metabolite of imatinib. Imatinib is a drug used in the treatment of chronic myeloid leukemia (CML). It works by inhibiting the activity of certain enzymes that are responsible for the growth of cancer cells. N-desmethyl imatinib is a major metabolite of imatinib and is believed to have similar pharmacological properties.
N-Desmethyl Imatinib D8 is used as a reference standard in pharmaceutical research and development. It is also used in pharmacokinetic studies to determine the metabolism and elimination of imatinib and its metabolites. The deuterium atoms present in N-Desmethyl Imatinib D8 can be used as a tracer to study the pharmacokinetics of imatinib in vivo.
The chemical formula of N-Desmethyl Imatinib D8 is C26H20D8N7O, and its molecular weight is 455.53 g/mol. It is a white to off-white powder that is soluble in dimethyl sulfoxide and methanol. The compound is stable under normal storage conditions and does not require any special handling procedures.
In conclusion, N-Desmethyl Imatinib D8 is a deuterated form of N-desmethyl imatinib that is used as a reference standard in pharmaceutical research and development. It is also used in pharmacokinetic studies to determine the metabolism and elimination of imatinib and its metabolites.
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Related Compounds
Imatinib D8 | Desmethyl imatinib D4 | Imatinib D3 | Gleevec-d8 Mesylate (Imatinib-d8 Mesylate) | Imatinib D4 | Imatinib Para-diaminomethylbenzene Impurity-d3 | Imatinib-(4-desmethyl phenyl)-impurity-d4 | Imatinib 13C D3 |