Isoniazid D4

Isoniazid D4 is a deuterated form of the drug Isoniazid, which is commonly used for the treatment of tuberculosis. The deuterated form is used in pharmacokinetic studies to determine the metabolism and elimination of the drug in the human body. The drug works by inhibiting the synthesis of mycolic acids in the cell wall of the tuberculosis bacterium, which makes it an important drug for the treatment of the disease. Isoniazid D4 is a white crystalline powder with a molecular weight of 144.20 g/mol and a chemical formula of C6H4D4N2O. It is soluble in water and ethanol, and has a melting point of 170-173°C. The deuterium atoms in the drug provide a unique way to track the metabolism and elimination of the drug in the body, as deuterium is a non-radioactive isotope of hydrogen. The drug is typically administered orally, and is absorbed quickly in the gastrointestinal tract. It is metabolized in the liver and excreted in the urine. The drug has a half-life of approximately 1-3 hours in the body. Isoniazid D4 is a valuable tool for pharmacokinetic studies of Isoniazid, as it allows researchers to track the metabolism and elimination of the drug in the body. This information can be used to optimize dosing regimens and improve treatment outcomes for patients with tuberculosis.