Itraconazole D3
| Product Name | Itraconazole D3 |
|---|---|
| Alternate Names | Itraconazole Stable Isotopes, Stable Isotopes of Itraconazole |
| CAT No. | CS-O-06691 |
| CAS No. | 1217512-35-0 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 708.65 g/mol |
| Mol. For. | C₃₅H₃₅D₃Cl₂N₈O₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Itraconazole |
| Purity | 95% |
| Therapeutic | Anti-Fungals |
| Smileys | CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl |
| Canonical Smiles | CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl |
| InchIKey | VHVPQPYKVGDNFY-BMSJAHLVSA-N |
| Inchl | InChI=1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/i2D3 |
| IUPAC | 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(1,1,1-trideuteriobutan-2-yl)-1,2,4-triazol-3-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Itraconazole D3 is a deuterated form of Itraconazole, which is a triazole antifungal agent used to treat systemic fungal infections. This medication is available in capsule and oral solution forms and is typically prescribed for patients with fungal infections that have not responded to other treatments.
Itraconazole D3 works by inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane. This ultimately leads to the disruption of the fungal cell membrane leading to its death. The deuterated form, Itraconazole D3, is used in pharmacokinetic studies to track the drug's distribution and metabolism in the body.
Chemically, Itraconazole D3 is an analog of itraconazole, with three of its hydrogen atoms replaced with deuterium. This substitution does not affect the pharmacological action of the drug but instead provides better clarity in mass spectrometry and other analytical methods.
Itraconazole D3 is typically administered orally, with a recommended dosage of 200mg once daily for 7 to 28 days depending on the severity of the infection. Patients with liver or kidney disease may require a dose adjustment, and caution should be taken when administering this medication to patients on certain other medications or with certain medical conditions.
In conclusion, Itraconazole D3 is a useful tool in the study of the pharmacokinetics of itraconazole. It is an effective antifungal agent that is commonly used to treat systemic fungal infections. However, it is important to follow the recommended dosage and monitor patients closely for potential adverse effects.
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Related Compounds
Itraconazole D9 | Hydroxy Itraconazole D8 | Hydroxy Itraconazole-d5 | Itraconazole D5 | Keto Itraconazole-d8 | Hydroxy Itraconazole D6 |