(S)-Lercanidipine D3 Hydrochloride

Product Name (S)-Lercanidipine D3 Hydrochloride
Alternate Names Lercanidipine Stable Isotopes, Stable Isotopes of Lercanidipine
CAT No. CS-O-06714
CAS No. 1217740-02-7
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 651.21 g/mol
Mol. For. C₃₆H₃₉D₃ClN₃O₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Lercanidipine
Purity 95%
Therapeutic Anti-Hypertensives
Smileys O=C(C([C@@H](C1=CC([N](=O)=O)=CC=C1)C(C(OC)=O)=C(C)N2)=C2C)OC(C)(C)CN(C([2H])([2H])[2H])CCC(C3=CC=CC=C3)C4=CC=CC=C4.Cl
Canonical Smiles CC1=C(C(C(=C(N1)C)C(=O)OC(C)(C)CN(C)CCC(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC.Cl
InchIKey WMFYOYKPJLRMJI-RFTUCFSWSA-N
Inchl InChI=1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H/t33-;/m0./s1/i5D3;
IUPAC 5-O-[1-[3,3-diphenylpropyl(trideuteriomethyl)amino]-2-methylpropan-2-yl] 3-O-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
Controlled No
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(S)-Lercanidipine D3 Hydrochloride is a chemical compound that belongs to the dihydropyridine class of calcium channel blockers. It is a deuterated form of (S)-Lercanidipine Hydrochloride, which is used for the treatment of hypertension and angina pectoris. It is a white or off-white crystalline powder that is soluble in water and ethanol. The mechanism of action of (S)-Lercanidipine D3 Hydrochloride involves the blockade of L-type calcium channels in the smooth muscle cells of blood vessels, causing vasodilation and lowering of blood pressure. The deuterated form of the drug is often used in pharmacokinetic studies to determine the bioavailability and metabolism of the drug in humans. The recommended dosage of (S)-Lercanidipine D3 Hydrochloride is 10 mg to 20 mg once daily, with a maximum dose of 20 mg per day. It is usually administered orally, and its effects can last for up to 24 hours. There are several precautions and contraindications associated with the use of (S)-Lercanidipine D3 Hydrochloride. Patients with severe liver or kidney dysfunction, hypotension, or a history of allergic reactions to dihydropyridines should avoid taking the drug. It may also interact with other medications, such as beta-blockers and digoxin. In conclusion, (S)-Lercanidipine D3 Hydrochloride is a potent calcium channel blocker that is used for the treatment of hypertension and angina pectoris. Its deuterated form is often used in pharmacokinetic studies, and it should be used with caution in patients with certain medical conditions or who are taking other medications.

Related Compounds

R(-)-Lercanidipine D3 Hydrochloride | Lercanidipine 13C D3 Hydrochloride | Lercanidipine D3 Hydrochloride |

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