Lumefantrine D18
| Product Name | Lumefantrine D18 |
|---|---|
| Alternate Names | Lumefantrine Stable Isotopes, Stable Isotopes of Lumefantrine |
| CAT No. | CS-O-06738 |
| CAS No. | 1185240-53-2 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 547.05 g/mol |
| Mol. For. | C₃₀H₁₄D₁₈Cl₃NO |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Lumefantrine |
| Purity | 99.02 |
| Smileys | CCCCN(CCCC)CC(C1=CC(=CC2=C1C3=C(C2=CC4=CC=C(C=C4)Cl)C=C(C=C3)Cl)Cl)O |
| Canonical Smiles | CCCCN(CCCC)CC(C1=CC(=CC2=C1C3=C(C2=CC4=CC=C(C=C4)Cl)C=C(C=C3)Cl)Cl)O |
| InchIKey | DYLGFOYVTXJFJP-OASVJRPASA-N |
| Inchl | InChI=1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15-/i1D3,2D3,3D2,4D2,5D2,6D2,13D2,14D2 |
| IUPAC | 2-[bis(1,1,2,2,3,3,4,4,4-nonadeuteriobutyl)amino]-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Lumefantrine D18 is a chemical compound used in the treatment of malaria. It is a white to pale yellow crystalline powder that is insoluble in water but soluble in organic solvents such as ethanol and ethyl acetate. Lumefantrine D18 is a derivative of artemisinin, which is a naturally occurring compound found in the Chinese medicinal plant Artemisia annua. Artemisinin is known for its antimalarial properties, and Lumefantrine D18 is one of the drugs that has been developed based on this compound.
Lumefantrine D18 is usually administered in combination with another antimalarial drug called artemether. The combination is known as artemether-lumefantrine and is used to treat uncomplicated malaria caused by Plasmodium falciparum, the most deadly form of malaria. Artemether-lumefantrine is taken orally in tablet form and is effective against both drug-resistant and non-resistant strains of the malaria parasite.
The mechanism of action of Lumefantrine D18 is not fully understood, but it is believed to inhibit the formation of hemozoin, a toxic substance that is produced by the malaria parasite. Hemozoin is essential for the survival of the parasite, and the inhibition of its formation leads to the death of the parasite. Lumefantrine D18 has a long half-life, which means that it remains in the body for a long time and provides sustained antimalarial activity.
In conclusion, Lumefantrine D18 is an important antimalarial drug that is used in combination with artemether to treat malaria. Its chemical properties and mechanism of action make it an effective treatment for both drug-resistant and non-resistant strains of the malaria parasite.
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Related Compounds
N-Desbutyl Lumefantrine D9 | Lumefantrine D9 |