Lumefantrine D9
| Product Name | Lumefantrine D9 |
|---|---|
| Alternate Names | Lumefantrine Stable Isotopes, Stable Isotopes of Lumefantrine |
| CAT No. | CS-O-06739 |
| CAS No. | 82186-77-4(Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 538.00 g/mol |
| Mol. For. | C₃₀H₂₃D₉Cl₃NO |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Lumefantrine |
| Purity | 95% |
| Smileys | OC(C1=CC(Cl)=CC2=C1C3=CC=C(Cl)C=C3/C2=C/C4=CC=C(Cl)C=C4)CN(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])CCCC |
| Canonical Smiles | CCCCN(CCCC)CC(C1=CC(=CC2=C1C3=C(C2=CC4=CC=C(C=C4)Cl)C=C(C=C3)Cl)Cl)O |
| InchIKey | DYLGFOYVTXJFJP-MYYYXRDXSA-N |
| Inchl | InChI=1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15- |
| IUPAC | 2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Lumefantrine D9 is a deuterated variant of Lumefantrine, a medication used to treat malaria. Lumefantrine D9 is used as a research tool in drug metabolism and pharmacokinetic studies. It is employed in quantitative analysis of Lumefantrine in biological samples by liquid chromatography-mass spectrometry (LC-MS).
Lumefantrine D9 has a molecular formula of C30H31D9Cl3NO and a molar mass of 548.11 g/mol. It is a white to off-white crystalline powder that is sparingly soluble in water and slightly soluble in ethanol. Lumefantrine D9 is a chiral compound with four stereoisomers. It is a racemic mixture of the R and S enantiomers.
Lumefantrine D9 is metabolized in the liver by the cytochrome P450 system. It is primarily eliminated from the body through feces. The elimination half-life of Lumefantrine D9 is approximately 4-6 days. Lumefantrine D9 is a potent inhibitor of hERG channels and prolongs the QT interval of the heart. Therefore, caution should be exercised when administering Lumefantrine D9 to patients with known cardiac disorders.
In conclusion, Lumefantrine D9 is a useful research chemical with applications in drug metabolism and pharmacokinetic studies. Its chemical properties and metabolic pathways have been extensively studied, making it a valuable tool in the development of new antimalarial drugs.
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Related Compounds
Lumefantrine D18 | N-Desbutyl Lumefantrine D9 |