Methotrexate D3
| Product Name | Methotrexate D3 |
|---|---|
| Alternate Names | Methotrexate Stable Isotopes, Stable Isotopes of Methotrexate |
| CAT No. | CS-O-06766 |
| CAS No. | 432545-63-6 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 457.46 g/mol |
| Mol. For. | C₂₀H₁₉D₃N₈O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Methotrexate |
| Purity | Not less than 90 % |
| Therapeutic | Immunosuppressants |
| Smileys | [2H]C([2H])([2H])N(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O |
| Canonical Smiles | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O |
| InchIKey | FBOZXECLQNJBKD-FIBGUPNXSA-N |
| Inchl | InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/i1D3 |
| IUPAC | 2-[[4-[(2,4-diaminopteridin-6-yl)methyl-(trideuteriomethyl)amino]benzoyl]amino]pentanedioic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Methotrexate D3 is a medication that is commonly used in the treatment of various types of cancer such as leukemia, lymphoma, and breast cancer. It is also used to treat autoimmune disorders such as rheumatoid arthritis and psoriasis. Methotrexate D3 works by interfering with the growth and division of cancer cells, which ultimately leads to their death. It is a chemotherapeutic agent that is typically administered by injection or oral tablet.
The chemical structure of Methotrexate D3 is similar to that of folic acid, which is an essential vitamin required for DNA synthesis. Methotrexate D3 acts by inhibiting the enzyme dihydrofolate reductase, which is responsible for converting dihydrofolic acid to tetrahydrofolic acid. This, in turn, prevents the synthesis of thymidylate, a nucleotide required for DNA replication. By blocking this process, Methotrexate D3 effectively inhibits the growth of cancer cells.
Methotrexate D3 is a potent medication that can cause several side effects, including nausea, vomiting, and hair loss. It can also suppress the immune system, which can increase the risk of infections. Patients taking Methotrexate D3 require regular blood tests to monitor their liver function and blood cell counts to ensure that the medication is not causing any adverse effects.
In conclusion, Methotrexate D3 is a valuable medication in the treatment of cancer and autoimmune disorders. Its chemical structure and mechanism of action make it an effective chemotherapeutic agent, although it can also cause significant side effects. Patients taking Methotrexate D3 should be closely monitored by healthcare professionals to ensure its safe and effective use.
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Related Compounds
Methotrexate D7 Triglutamate | Methotrexate 13CD3 | Methotrexate-d3 Dimethyl Ester |