Metoclopramide D3

Product Name Metoclopramide D3
Alternate Names Metoclopramide Stable Isotopes, Stable Isotopes of Metoclopramide
CAT No. CS-O-06769
CAS No. 1216522-89-2
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 302.81 g/mol
Mol. For. C₁₄H₁₉D₃ClN₃O₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Metoclopramide
Purity 95%
Therapeutic Anti-Emetics
Smileys O=C(C(C=C(Cl)C(N)=C1)=C1OC([2H])([2H])[2H])NCCN(CC)CC
Canonical Smiles CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl
InchIKey TTWJBBZEZQICBI-HPRDVNIFSA-N
Inchl InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)/i3D3
IUPAC 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(trideuteriomethoxy)benzamide
Controlled No
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Metoclopramide D3 is a deuterated form of the drug metoclopramide, which is a medication used to treat gastrointestinal disorders such as nausea, vomiting, and reflux disease. Metoclopramide D3 is chemically similar to metoclopramide but contains three deuterium atoms, which are stable isotopes of hydrogen. This modification does not alter the therapeutic properties of the drug, but it allows for easier detection and quantification of the drug in biological samples. Metoclopramide D3 acts by blocking dopamine receptors in the brain and gut, which reduces nausea and vomiting symptoms. It also stimulates the muscles of the gastrointestinal tract, which helps to move food and fluids through the digestive system. The drug is administered orally or intravenously, and its effects are typically seen within 30 minutes to an hour. Metoclopramide D3 is primarily metabolized by the liver and excreted in the urine. The drug has a half-life of 5-6 hours in adults, and its duration of action is typically 4-6 hours. It is important to note that metoclopramide can have side effects such as drowsiness, restlessness, and muscle spasms. It should be used with caution in patients with a history of seizures or Parkinson's disease. In conclusion, Metoclopramide D3 is a useful tool for pharmacokinetic studies and drug monitoring in patients receiving metoclopramide therapy. Its chemical properties and mechanism of action make it an effective treatment option for gastrointestinal disorders.

Related Compounds

Metoclopramide-d3 N-Oxide | N-Acetyl Metoclopramide-d3 | Metoclopramide 13C6 |

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