Naftopidil D7
| Product Name | Naftopidil D7 |
|---|---|
| Alternate Names | Naftopidil Stable Isotopes, Stable Isotopes of Naftopidil |
| CAT No. | CS-O-06797 |
| CAS No. | 57149-07-2(Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 399.53 g/mol |
| Mol. For. | C₂₄H₂₁D₇N₂O₃ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Naftopidil |
| Smileys | OC(CN1CCN(C(C=CC=C2)=C2OC)CC1)COC3=C([2H])C([2H])=C([2H])C4=C([2H])C([2H])=C([2H])C([2H])=C34 |
| Canonical Smiles | COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O |
| InchIKey | HRRBJVNMSRJFHQ-UHFFFAOYSA-N |
| Inchl | InChI=1S/C24H28N2O3/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23/h2-12,20,27H,13-18H2,1H3 |
| IUPAC | 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Naftopidil D7 is a deuterated analogue of the drug Naftopidil, which is commonly used in the treatment of benign prostatic hyperplasia (BPH). Naftopidil D7 is a selective alpha-1 adrenoceptor antagonist, which means it blocks the action of the alpha-1 receptors in the prostate gland, bladder neck, and urethra. This results in relaxation of the smooth muscle in these areas, which leads to improved urine flow and reduced symptoms of BPH.
Chemically, Naftopidil D7 is a deuterated derivative of Naftopidil, with seven deuterium atoms incorporated into its molecular structure. Deuterium is a stable isotope of hydrogen, and its incorporation into the drug molecule provides several advantages, including improved stability, decreased metabolic degradation, and increased bioavailability.
Naftopidil D7 is typically administered orally, with a recommended dosage of 25 mg per day. The drug is rapidly absorbed from the gastrointestinal tract and reaches peak plasma concentrations within two hours of administration. Naftopidil D7 is metabolized in the liver and excreted primarily in the urine.
Overall, Naftopidil D7 is a highly effective and well-tolerated treatment option for BPH. Its selective alpha-1 blocking activity and deuterated structure provide several advantages over other drugs in this class.
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