Nifedipine D6
| Product Name | Nifedipine D6 |
|---|---|
| Alternate Names | Nifedipine Stable Isotopes, Stable Isotopes of Nifedipine |
| CAT No. | CS-O-06813 |
| CAS No. | 1188266-14-9 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 352.37 g/mol |
| Mol. For. | C₁₇H₁₂D₆N₂O₆ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Nifedipine |
| Purity | Not less than 95 % |
| Therapeutic | Anti-Hypertensives |
| Smileys | [2H]C([2H])([2H])OC(=O)C1=C(NC(=C(C1C2=CC=CC=C2[N+](=O)[O-])C(=O)OC([2H])([2H])[2H])C)C |
| Canonical Smiles | CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC |
| InchIKey | HYIMSNHJOBLJNT-LIJFRPJRSA-N |
| Inchl | InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3/i3D3,4D3 |
| IUPAC | bis(trideuteriomethyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Nifedipine D6 is a deuterated analog of the calcium channel blocker nifedipine that is commonly used for the treatment of hypertension, angina, and other cardiovascular conditions. This compound has the same molecular formula as nifedipine (C17H18N2O6), but with six of its hydrogen atoms replaced by deuterium atoms.
Nifedipine D6 works by blocking the influx of calcium ions into vascular smooth muscle cells and cardiac cells, leading to vasodilation and reduced cardiac contractility. This results in decreased blood pressure and improved blood flow to the heart.
The deuterium substitution in Nifedipine D6 allows for its incorporation into metabolic studies and pharmacokinetic studies, as it can be easily distinguished from the non-deuterated compound in mass spectrometry analyses.
Nifedipine D6 is typically administered orally in the form of extended-release tablets, with a typical daily dose ranging from 20-60 mg. It is important to note that this compound should not be used in patients with hypotension, aortic stenosis, or acute myocardial infarction. Common side effects of Nifedipine D6 include headache, dizziness, flushing, and peripheral edema.
Overall, Nifedipine D6 is a useful tool in cardiovascular research and provides valuable insights into the pharmacokinetics and metabolism of nifedipine.
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Related Compounds
Nifedipine 13C8 | Nifedipine dehydro nitroso-d6 | Dehydronifedipine 13C8 | Dehydro Nifedipine D6 | Nifedipine nitroso-d6 | m-Nifedipine-d6 |