Propafenone-d7 (propyl-d7) hydrochloride
| Product Name | Propafenone-d7 (propyl-d7) hydrochloride |
|---|---|
| Alternate Names | Propafenone Stable Isotopes, Stable Isotopes of Propafenone |
| CAT No. | CS-O-06889 |
| CAS No. | 1219799-06-0 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 384.95 g/mol |
| Mol. For. | C₂₁H₂₁D₇ClNO₃ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Propafenone |
| Purity | 95% |
| Smileys | OC(CNC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])COC(C=CC=C1)=C1C(CCC2=CC=CC=C2)=O.Cl |
| Canonical Smiles | CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl |
| InchIKey | XWIHRGFIPXWGEF-YYEJEILISA-N |
| Inchl | InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H/i1D3,2D2,14D2; |
| IUPAC | 1-[2-[3-(1,1,2,2,3,3,3-heptadeuteriopropylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one;hydrochloride |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Propafenone-d7 hydrochloride, also known as propyl-d7 hydrochloride, is a deuterated form of the antiarrhythmic drug propafenone. It is a selective blocker of cardiac sodium channels and also has beta-blocking properties. Propafenone-d7 hydrochloride is used in the treatment of various types of cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia.
Chemically, propafenone-d7 hydrochloride is a substituted arylalkylamine, containing a propyl group. The deuterium atoms in the propyl group are stable isotopes of hydrogen, which are used as tracers in pharmacokinetic studies. Propafenone-d7 hydrochloride is a white crystalline powder that is soluble in water and ethanol.
The pharmacological effects of propafenone-d7 hydrochloride are similar to those of the non-deuterated propafenone. It works by blocking the fast sodium channels in the heart, which slows down the conduction of electrical impulses and helps to restore normal heart rhythm. It also has beta-blocking properties, which reduce the heart rate and the workload on the heart.
Propafenone-d7 hydrochloride is administered orally and is rapidly absorbed from the gastrointestinal tract. It has a half-life of about 6-10 hours and is metabolized in the liver. The drug is excreted mainly in the urine, with a small amount being excreted in the feces. The deuterium-labeled propyl group in propafenone-d7 hydrochloride allows for accurate measurement of its pharmacokinetics, which is useful in drug development and clinical research.
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Related Compounds
Propafenone-d7 (propyl-d7) | Depropylamino Hydroxy Propafenone D5 | N-Depropyl Propafenone-d5 Oxalate Salt | N-nitroso-propafenone D7 | Propafenone-d5 (propoxy-d5) hydrochloride | Propafenone-d5 (phenyl-d5) hydrochloride | Despropyl Propafenone-d6 Oxalate | Propafenone Dimer Impurity D10 | N-Nitroso Propafenone (2,2,3,3,3-Propyl-D5) | Depropylamino Chloro Propafenone-d5 | Propafenone-d5 (n-propyl-2,2,3,3,3-d5) Hydrochloride |