Rilpivirine D6
| Product Name | Rilpivirine D6 |
|---|---|
| Alternate Names | Rilpivirine Stable Isotopes, Stable Isotopes of Rilpivirine |
| CAT No. | CS-O-06927 |
| CAS No. | 1312424-26-2 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 372.46 g/mol |
| Mol. For. | C₂₂H₁₂D₆N₆ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Rilpivirine |
| Purity | 95% |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | N#C/C=C/C1=CC(C([2H])([2H])[2H])=C(C(C([2H])([2H])[2H])=C1)NC2=NC(NC3=CC=C(C#N)C=C3)=NC=C2 |
| Canonical Smiles | CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)C=CC#N |
| InchIKey | YIBOMRUWOWDFLG-XDMLVRQJSA-N |
| Inchl | InChI=1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+/i1D3,2D3 |
| IUPAC | 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-bis(trideuteriomethyl)anilino]pyrimidin-2-yl]amino]benzonitrile |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Rilpivirine D6 is a deuterated form of rilpivirine, an FDA-approved antiretroviral medication used to treat HIV infection. It is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that works by inhibiting the activity of the reverse transcriptase enzyme, which is essential for the replication of the virus.
The deuterated form of rilpivirine, Rilpivirine D6, is used in pharmacokinetic studies to determine the metabolism, distribution, and excretion of the drug in the body. Deuterium is an isotope of hydrogen that is twice as heavy as the regular hydrogen atom, and its incorporation into the drug molecule allows for more accurate measurement of the drug's pharmacokinetic properties.
Rilpivirine D6 has a similar chemical structure to rilpivirine, with the addition of six deuterium atoms. Its chemical formula is C22H16D6N5O3, and its molecular weight is 422.49 g/mol. It is a white to off-white powder that is soluble in dimethyl sulfoxide (DMSO) and ethanol.
Like rilpivirine, Rilpivirine D6 can cause side effects such as nausea, vomiting, diarrhea, headache, and dizziness. It is important to take the medication as prescribed and to notify a healthcare provider if any side effects occur.
Rilpivirine D6 is a valuable tool in the study of HIV medication pharmacokinetics, and its use can help improve the efficacy and safety of HIV treatment regimens.
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Related Compounds
Z-Rilpivirine-d4 | E-Rilpivirine-d4 |