Sildenafil D3

Product Name Sildenafil D3
Alternate Names Sildenafil Stable Isotopes, Stable Isotopes of Sildenafil
CAT No. CS-O-06964
CAS No. 1126745-90-1
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 477.59 g/mol
Mol. For. C₂₂H₂₇D₃N₆O₄S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Sildenafil
Purity Not less than 98 %
Therapeutic Erectile dysfunction
Smileys CCOC1=C(C(NC2=C3N(C)N=C2CCC)=NC3=O)C=C([S](=O)(N4CCN(C([2H])([2H])[2H])CC4)=O)C=C1
Canonical Smiles CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
InchIKey BNRNXUUZRGQAQC-HPRDVNIFSA-N
Inchl InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)/i3D3
IUPAC 5-[2-ethoxy-5-[4-(trideuteriomethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
Controlled No
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Sildenafil D3 is a derivative of sildenafil, which is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. The D3 form of sildenafil is a deuterated form, which means that some of the hydrogen atoms in the molecule are replaced with deuterium atoms. This modification increases the stability of the molecule and slows down its metabolism in the body, resulting in a longer half-life and more sustained effects. The chemical formula of Sildenafil D3 is C22H30D3N6O4S, and its molecular weight is 475.64 g/mol. It works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP) in the penis and lungs. By inhibiting PDE5, sildenafil D3 increases the levels of cGMP, which causes relaxation of the smooth muscles in the blood vessels and allows for increased blood flow to the penis and lungs. The recommended dosage of Sildenafil D3 varies depending on the individual's condition and response to treatment. It is typically taken orally, 30 minutes to 4 hours before sexual activity, and should not be taken more than once per day. Sildenafil D3 is generally well-tolerated, but like all medications, it may cause side effects such as headache, dizziness, flushing, and indigestion. It should not be taken by individuals who are allergic to sildenafil or any of its ingredients, have a history of heart disease, or are taking medications that interact with PDE5 inhibitors. It is important to consult with a healthcare provider before taking Sildenafil D3 to ensure the medication is safe and appropriate for the individual's needs.

Related Compounds

Homo sildenafil-d5 (ethyl-d5) | Pyrazole N-Demethyl Sildenafil-d3 | Propoxyphenyl ​thiohydroxyhomosilde​nafil-d4 | Methisosildenafil-d4 | Desethyl Sildenafil D3 | Sildenafil dimer-D8 | N-desmethyl Sildenafil D8 | Thiosildenafil-d3 | Sildenafil D8 |

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