Tolcapone D4

Product Name Tolcapone D4
Alternate Names Tolcapone Stable Isotopes, Stable Isotopes of Tolcapone
CAT No. CS-O-07014
CAS No. 1246816-93-2
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 277.27 g/mol
Mol. For. C14H7D4NO5
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Tolcapone
Purity 98.6
Therapeutic Anti-Parkinsons
Smileys CC1=CC=C(C=C1)C(=O)C2=CC(=C(C(=C2)O)O)[N+](=O)[O-]
Canonical Smiles CC1=CC=C(C=C1)C(=O)C2=CC(=C(C(=C2)O)O)[N+](=O)[O-]
InchIKey MIQPIUSUKVNLNT-QFFDRWTDSA-N
Inchl InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3/i2D,3D,4D,5D
IUPAC (3,4-dihydroxy-5-nitrophenyl)-(2,3,5,6-tetradeuterio-4-methylphenyl)methanone
Controlled No
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Tolcapone D4 is a stable isotope-labeled form of Tolcapone, a drug used to treat Parkinson's disease. It works by inhibiting the activity of an enzyme called catechol-O-methyltransferase (COMT), which breaks down the neurotransmitter dopamine in the brain. By blocking the activity of COMT, Tolcapone D4 helps to increase the levels of dopamine in the brain, leading to improved symptoms of Parkinson's disease. Tolcapone D4 is typically administered orally, either alone or in combination with other medications used to treat Parkinson's disease. The recommended dosage of Tolcapone D4 depends on the severity of the patient's symptoms and their response to treatment. Chemically, Tolcapone D4 is a white to off-white crystalline powder that is soluble in water. It has a molecular formula of C14H4D4N2O5 and a molecular weight of 309.31 g/mol. Tolcapone D4 is a deuterium-labeled analog of Tolcapone, with four deuterium atoms replacing four hydrogen atoms in the molecule. This labeling makes it useful in pharmacokinetic studies, as it allows researchers to track the drug's distribution and metabolism in the body. While Tolcapone D4 is generally well-tolerated, it can cause side effects such as diarrhea, nausea, and dry mouth. In rare cases, it may also cause liver problems, so patients taking Tolcapone D4 should be monitored regularly for signs of liver damage. Overall, Tolcapone D4 is an effective medication for treating Parkinson's disease, and its stable isotope labeling makes it a valuable tool for pharmacological research.

Related Compounds

Tolcapone-D7 |

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